Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pseudoephedrine
Drug ID BADD_D01876
Description Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.[A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]
Indications and Usage Pseudoephedrine is a sympathomimetic amine used for its decongestant activity.[L11031,L11037,L11040,L11046,L11052,L11058,L11061]
Marketing Status approved
ATC Code R01BA02
DrugBank ID DB00852
KEGG ID D08449
MeSH ID D054199
PubChem ID 7028
TTD Drug ID D00HHS
NDC Product Code 57218-500
UNII 7CUC9DDI9F
Synonyms Pseudoephedrine | Pseudoephedrine Hydrochloride | Pseudoephedrine HCl | Sudafed | Isoephedrine | Threo Isomer of Ephedrine | Ephedrine Threo Isomer
Chemical Information
Molecular Formula C10H15NO
CAS Registry Number 90-82-4
SMILES CC(C(C1=CC=CC=C1)O)NC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Abdominal pain lower07.01.05.0100.000326%Not Available
Agitation19.06.02.001; 17.02.05.012--
Anxiety19.06.02.0020.001110%
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.010--Not Available
Blood pressure increased13.14.03.005--Not Available
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.009--Not Available
Colitis ischaemic24.04.08.012; 07.08.01.0040.000490%Not Available
Confusional state19.13.01.001; 17.02.03.0050.000718%
Death08.04.01.0010.000816%
Dermatitis23.03.04.002--Not Available
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.0020.000326%Not Available
Disorientation19.13.01.002; 17.02.05.0150.000326%Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.0060.000326%
Drug abuse19.07.06.0100.000979%Not Available
Drug dependence19.07.06.0110.000979%Not Available
Drug hypersensitivity10.01.01.0010.004440%Not Available
Dry mouth07.06.01.0020.000718%
Dysarthria19.19.03.001; 17.02.08.001--
Dyskinesia17.01.02.006--
Dyspnoea02.11.05.003; 22.02.01.0040.000882%
Extrasystoles02.03.02.003--Not Available
Face oedema10.01.05.002; 23.04.01.004; 08.01.07.003--
Fatigue08.01.01.002--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
The 1th Page    1 2 3    Next   Last    Total 3 Pages