Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pseudoephedrine
Drug ID BADD_D01876
Description Pseudoephedrine is structurally related to [ephedrine] but exerts a weaker effect on the sympathetic nervous system.[A188820,A188823] Both drugs naturally occur in in ephedra plant which have a history of use in traditional Eastern medicine and were first researched in the west in 1889.[A188823] The decongestant effect of pseudoephedrine was described in dogs in 1927.[A188823]
Indications and Usage Pseudoephedrine is a sympathomimetic amine used for its decongestant activity.[L11031,L11037,L11040,L11046,L11052,L11058,L11061]
Marketing Status approved
ATC Code R01BA02
DrugBank ID DB00852
KEGG ID D08449
MeSH ID D054199
PubChem ID 7028
TTD Drug ID D00HHS
NDC Product Code 57218-500
UNII 7CUC9DDI9F
Synonyms Pseudoephedrine | Pseudoephedrine Hydrochloride | Pseudoephedrine HCl | Sudafed | Isoephedrine | Threo Isomer of Ephedrine | Ephedrine Threo Isomer
Chemical Information
Molecular Formula C10H15NO
CAS Registry Number 90-82-4
SMILES CC(C(C1=CC=CC=C1)O)NC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.0010.000816%
Hypokinesia17.01.02.009--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.008--
Loss of consciousness17.02.04.004--Not Available
Malaise08.01.01.003--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Palpitations02.11.04.0120.001045%
Paraesthesia23.03.03.094; 17.02.06.005--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Retinopathy06.10.02.001; 24.03.07.003--
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.0010.001143%
Sinus congestion22.04.06.001--Not Available
Sinus tachycardia02.03.03.010--
Skin discolouration23.03.03.005--Not Available
Skin exfoliation23.03.07.003--Not Available
Somnolence17.02.04.006; 19.02.05.003--
Tachycardia02.03.02.007--Not Available
Tremor17.01.06.002--
Urinary retention20.02.02.011--
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
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