Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Pyrilamine
Drug ID BADD_D01885
Description Mepyramine, or pyrilamine, targets the H1 receptor. It is a first generation antihistamine. However, it rapidly permeates the brain and so often causes drowsiness as a side effect. It has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions.
Indications and Usage Indicated for the treatment of allergic conditions, symptomatic relief of hypersensitivity reaction, and treatment of pruritic skin disorders.
Marketing Status approved; vet_approved
ATC Code R06AC01; D04AA02
DrugBank ID DB06691
KEGG ID D08183; D05660
MeSH ID D011738
PubChem ID 4992
TTD Drug ID D08JZS
NDC Product Code 66620-100
UNII HPE317O9TL
Synonyms Pyrilamine | Mepyramine | Pyranisamine | Kriptin | Mepyramine Maleate | Maleate, Mepyramine | Pyrilamine Maleate | Maleate, Pyrilamine | Boots Bite & Sting Relief | Anthisan
Chemical Information
Molecular Formula C17H23N3O
CAS Registry Number 91-84-9
SMILES CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin sensitisation23.03.03.052; 10.02.01.038--Not Available
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