Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Quinaprilat
Drug ID BADD_D01892
Description The active metabolite of the prodrug [quinapril].
Indications and Usage Not Available
Marketing Status experimental
ATC Code Not Available
DrugBank ID DB14217
KEGG ID D03773
MeSH ID C054501
PubChem ID 107994
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 34SSX5LDE5
Synonyms quinaprilat | 2-(2-((1-carboxy-3-phenylpropyl)amino)-1-oxopropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid | quinaprilat, (3S-(2(R*(R*)),3R*))-isomer | CI 928 | CI-928
Chemical Information
Molecular Formula C23H26N2O5
CAS Registry Number 82768-85-2
SMILES CC(C(=O)N1CC2=CC=CC=C2CC1C(=O)O)NC(CCC3=CC=CC=C3)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.006163%Not Available
Abdominal pain07.01.05.002--
Acute myocardial infarction24.04.04.001; 02.02.02.0010.002719%Not Available
Agranulocytosis01.02.03.001--Not Available
Alopecia23.02.02.001--
Amblyopia06.02.01.001--Not Available
Anaphylactic reaction10.01.07.001; 24.06.03.0060.002719%
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.0020.001813%
Angioedema10.01.05.009; 22.04.02.008; 23.04.01.0010.023382%Not Available
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.0010.004894%Not Available
Back pain15.03.04.005--
Blood urea increased13.13.01.006--Not Available
Cardiac failure congestive02.05.01.0020.009969%Not Available
Cardiogenic shock24.06.02.006; 02.05.01.003--Not Available
Cerebrovascular accident17.08.01.007; 24.03.05.0010.007250%
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.003988%Not Available
Condition aggravated08.01.03.0040.003625%Not Available
Constipation07.02.02.001--
Coronary artery disease24.04.04.006; 02.02.01.0010.005438%Not Available
Cough22.02.03.0010.036976%
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Dermatomyositis15.05.01.002; 10.04.04.027; 23.03.02.001--Not Available
Diabetes mellitus14.06.01.001; 05.06.01.0010.001813%Not Available
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
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