| Pharmaceutical Information |
| Drug Name |
Quinidine sulfate |
| Drug ID |
BADD_D01894 |
| Description |
An optical isomer of [quinine], extracted from the bark of the Cinchona tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular action potential, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission. |
| Indications and Usage |
For the treatment of ventricular pre-excitation and cardiac dysrhythmias |
| Marketing Status |
approved; investigational |
| ATC Code |
C01BA01 |
| DrugBank ID |
DB00908
|
| KEGG ID |
D02272
|
| MeSH ID |
D011802
|
| PubChem ID |
11069
|
| TTD Drug ID |
Not Available
|
| NDC Product Code |
12065-1701; 0185-1047; 0185-4346; 49452-6180 |
| UNII |
J13S2394HE
|
| Synonyms |
Quinidine | Chinidin | Apo-Quinidine | Apo Quinidine | Quinora | Quinidex | Quinidine Sulfate | Sulfate, Quinidine | Adaquin | Quincardine |
|
| Chemical Information |
| Molecular Formula |
C20H26N2O6S |
| CAS Registry Number |
50-54-4 |
| SMILES |
COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.OS(=O)(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
|
| Cerebral hypoperfusion | 24.03.05.008; 17.08.02.011; 12.02.01.014 | - | - | Not Available |
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