Drug Name |
Rabeprazole |
Drug ID |
BADD_D01898 |
Description |
Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion. |
Indications and Usage |
For the treatment of acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevention of gastroinetestinal bleeds with NSAID use. |
Marketing Status |
approved; investigational |
ATC Code |
A02BC04 |
DrugBank ID |
DB01129
|
KEGG ID |
D08463
|
MeSH ID |
D064750
|
PubChem ID |
5029
|
TTD Drug ID |
D0KL4J
|
NDC Product Code |
65162-724 |
UNII |
32828355LL
|
Synonyms |
Rabeprazole | 2-((4-(3-methoxypropoxy)-3-methylpyridin-2-yl)methylsulfinyl)-1H-benzimidazole | Dexrabeprazole | E 3810 | E3810 | Pariet | Rabeprazole Sodium | Sodium, Rabeprazole | 1H-Benzimidazole, 2-(((4-(3-methoxypropoxy)-3-methyl-2-pyridinyl)methyl)sulfinyl)-, Sodium Salt | Aciphex | LY-307640 | LY 307640 | LY307640 |