| Pharmaceutical Information |
| Drug Name |
Raltitrexed |
| Drug ID |
BADD_D01907 |
| Description |
Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase. |
| Indications and Usage |
For the treatment of malignant neoplasm of colon and rectum |
| Marketing Status |
approved; investigational |
| ATC Code |
L01BA03 |
| DrugBank ID |
DB00293
|
| KEGG ID |
D01064
|
| MeSH ID |
C068874
|
| PubChem ID |
135400182
|
| TTD Drug ID |
D01KKQ
|
| NDC Product Code |
Not Available |
| UNII |
FCB9EGG971
|
| Synonyms |
raltitrexed | N-(5-(N-(3,4-dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl)-N-methylamino)-2-thenoyl)-L-glutamic acid | ICI D1694 | ICI-D1694 | ZD 1694 | ZD1694 | ZD-1694 | D1694 | D 1694 | D-1694 | Tomudex |
|
| Chemical Information |
| Molecular Formula |
C21H22N4O6S |
| CAS Registry Number |
112887-68-0 |
| SMILES |
CC1=NC2=C(C=C(C=C2)CN(C)C3=CC=C(S3)C(=O)NC(CCC(=O)O)C(=O)O)C(=O)N1 |
| Chemical Structure |
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| ADRs Induced by Drug |
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