Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Raxibacumab
Drug ID BADD_D01918
Description Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
Indications and Usage Raxibacumab is indicated for the treatment of adult and pediatric patients with inhalational anthrax due to Bacillus anthracis in combination with appropriate antibacterial drugs, and for prophylaxis of inhalational anthrax when alternative therapies are not available or are not appropriate.
Marketing Status approved
ATC Code J06BC02
DrugBank ID DB08902
KEGG ID D05706
MeSH ID C542124
PubChem ID Not Available
TTD Drug ID Not Available
NDC Product Code 71655-103; 49401-080
UNII 794PGL549S
Synonyms raxibacumab | raxibacumab monoclonal antibody, human | abthrax
Chemical Information
Molecular Formula Not Available
CAS Registry Number 565451-13-0
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Amylase increased13.05.01.009--
Anaemia01.03.02.001--
Back pain15.03.04.005--
Blood creatine phosphokinase increased13.04.01.001--
Clonus17.02.05.002--Not Available
Dyspnoea02.11.05.003; 22.02.01.004--
Fatigue08.01.01.002--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Hypertension24.08.02.001--
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Lymphadenopathy01.09.01.002--Not Available
Muscle spasms15.05.03.004--
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pain in extremity15.03.04.010--
Palpitations02.11.04.012--
Prothrombin time prolonged13.01.02.012--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rash papular23.03.13.017--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Syncope24.06.02.012; 17.02.04.008; 02.11.04.015--
Telangiectasia24.03.03.003; 23.06.03.001--
Urticaria23.04.02.001; 10.01.06.001--
Vertigo17.02.12.002; 04.04.01.003--
Infusion site pain12.07.05.002; 08.02.05.014--Not Available
Antibody test13.06.03.009--Not Available
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