Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rimabotulinumtoxinb
Drug ID BADD_D01943
Description Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
Indications and Usage For the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.
Marketing Status approved; investigational
ATC Code Not Available
DrugBank ID DB00042
KEGG ID D02735
MeSH ID C096323
PubChem ID Not Available
TTD Drug ID D02FXK
NDC Product Code 10454-711; 10454-712; 10454-710
UNII 0Y70779M1F
Synonyms rimabotulinumtoxinB | rimabotulinum toxin B | rimabotulinumtoxin B | NeuroBloc | botulinum B toxin | botulinum toxin type B | botulinum neurotoxin B | Clostridium botulinum B toxin | Myobloc
Chemical Information
Molecular Formula Not Available
CAS Registry Number 93384-44-2
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abscess11.01.08.001--Not Available
Amblyopia06.02.01.001--Not Available
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Arthritis15.01.01.001--
Arthropathy15.01.01.003--Not Available
Asthenia08.01.01.001--Not Available
Back pain15.03.04.005--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Confusional state17.02.03.005; 19.13.01.001--
Constipation07.02.02.001--
Cough22.02.03.001--
Cyst16.02.02.002; 08.03.05.001--Not Available
Cystitis20.03.02.002; 11.01.14.001--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.007--
Dry mouth07.06.01.002--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Ecchymosis01.01.03.001; 24.07.06.002; 23.06.01.001--Not Available
Gastrointestinal disorder07.11.01.001--Not Available
Glossitis07.14.01.001--Not Available
Headache17.14.01.001--
Hernia08.01.04.001--Not Available
Hyperaesthesia23.03.03.080; 17.02.06.004--Not Available
Hypercholesterolaemia14.08.01.001--Not Available
Hypersensitivity10.01.03.003--
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