Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Rivastigmine
Drug ID BADD_D01955
Description Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Indications and Usage For the treatment of mild to moderate dementia associated with Parkinson's disease or of the Alzheimer's type.
Marketing Status approved; investigational
ATC Code N06DA03
DrugBank ID DB00989
KEGG ID D03822
MeSH ID D000068836
PubChem ID 77991
TTD Drug ID D0WY5Q
NDC Product Code 16714-117; 70710-1198; 72855-101; 0781-7304; 65372-1153; 82245-0107; 51956-0001; 51956-0002; 51991-898; 65162-826; 72855-102; 49706-1825; 0078-0503; 63629-2065; 65162-749; 65162-825; 0378-9072; 0781-7309; 12651-118; 64552-4021; 65015-819; 0078-0501; 63629-8846; 0378-9071; 70710-1196; 16714-115; 63629-2066; 50379-0014; 65862-982; 72855-100; 51956-0003; 51991-897; 51991-899; 0781-7313; 63629-2064; 0378-9070; 0078-0502; 16714-116; 63629-8807; 70710-1197
UNII PKI06M3IW0
Synonyms Rivastigmine | (S)-N-Ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate | RivastigmineTartrate | Rivastigmine Hydrogen Tartrate | Hydrogen Tartrate, Rivastigmine | Tartrate, Rivastigmine Hydrogen | Exelon | ENA 713 | 713, ENA | SDZ ENA 713 | 713, SDZ ENA | ENA 713, SDZ | ENA-713 | ENA713
Chemical Information
Molecular Formula C14H22N2O2
CAS Registry Number 123441-03-2
SMILES CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Drug interaction08.06.03.0010.002168%Not Available
Duodenitis haemorrhagic07.08.03.010; 24.07.02.0250.000542%Not Available
Dysarthria19.19.03.001; 17.02.08.0010.000813%
Dyskinesia17.01.02.0060.002981%
Dyspepsia07.01.02.0010.001084%
Dysphagia07.01.06.0030.008075%
Dystonia17.01.03.0010.000813%Not Available
Dysuria20.02.02.0020.000542%
Eating disorder19.09.01.008; 14.03.01.0080.001897%Not Available
Emphysema22.01.02.0020.000542%Not Available
Epilepsy17.12.03.0020.000813%Not Available
Erythema23.03.06.0010.006233%Not Available
Extrapyramidal disorder17.01.02.0070.000813%
Fall12.01.08.002--
Fatigue08.01.01.002--
Fear19.06.03.0010.000813%Not Available
Feeling abnormal08.01.09.0140.007588%Not Available
Fibroma16.02.02.010; 15.09.01.0040.001084%Not Available
Flank pain20.02.03.006; 15.03.04.003; 08.01.08.0070.000813%
Flatulence07.01.04.002--
Frequent bowel movements07.02.04.0020.000542%Not Available
Gait disturbance17.02.05.016; 08.01.02.002; 15.03.05.0130.005420%
Gastric ulcer07.04.03.0020.001897%
Gastritis07.08.02.0010.000813%
Gastrointestinal disorder07.11.01.0010.003469%Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal pain07.01.05.0050.001192%
Haematemesis24.07.02.011; 07.12.02.0020.001897%Not Available
Haemorrhagic stroke24.07.04.014; 17.08.01.0110.000813%Not Available
Hallucination19.10.04.0030.007696%
The 4th Page    First    Pre   4 5 6 7 8    Next   Last    Total 11 Pages
ADReCS-Target
Drug Name ADR Term Target
Tip:  Drug Name  ADR Term  Protein  Variation  Gene