Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rivastigmine tartrate
Drug ID BADD_D01956
Description Rivastigmine is a parasympathomimetic or cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer's type. Rivastigmine is a cholinesterase inhibitor that inhibits both butyrylcholinesterase and acetylcholinesterase.
Indications and Usage For the treatment of mild to moderate dementia associated with Parkinson's disease or of the Alzheimer's type.
Marketing Status approved; investigational
ATC Code N06DA03
DrugBank ID DB00989
KEGG ID D02558
MeSH ID D000068836
PubChem ID 6918078
TTD Drug ID D0WY5Q
NDC Product Code 0904-7107; 53104-7571; 33342-091; 62332-064; 62332-066; 71209-013; 71209-014; 71209-015; 72241-012; 33342-090; 51991-795; 55111-352; 62756-148; 65862-650; 46708-063; 46708-064; 55111-354; 62135-902; 62756-145; 62756-147; 60687-574; 62135-901; 62756-146; 72241-014; 75834-133; 65862-612; 65862-648; 33342-092; 62135-903; 72241-011; 75834-136; 49706-1826; 65862-651; 46708-066; 55111-066; 55111-353; 55111-355; 62332-063; 65862-649; 71209-012; 72241-013; 75834-135; 62704-0122; 65372-1152; 33342-089; 51991-793; 50379-0012; 46708-065; 51991-794; 62135-900; 62332-065; 75834-134; 51991-796
UNII 9IY2357JPE
Synonyms Rivastigmine | (S)-N-Ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate | RivastigmineTartrate | Rivastigmine Hydrogen Tartrate | Hydrogen Tartrate, Rivastigmine | Tartrate, Rivastigmine Hydrogen | Exelon | ENA 713 | 713, ENA | SDZ ENA 713 | 713, SDZ ENA | ENA 713, SDZ | ENA-713 | ENA713
Chemical Information
Molecular Formula C18H28N2O8
CAS Registry Number 129101-54-8
SMILES CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C.C(C(C(=O)O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Herpes simplex23.11.05.004; 11.05.02.001--Not Available
Herpes zoster23.11.05.005; 17.09.03.026; 11.05.02.003--
Hiccups22.12.01.001; 07.01.06.009--
Hip fracture15.08.03.001; 12.04.01.001--
Hypercholesterolaemia14.08.01.001--Not Available
Hyperglycaemia05.06.02.002; 14.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hyperkeratosis23.01.01.001--
Hyperkinesia17.01.02.008--Not Available
Hyperpyrexia08.05.02.002--Not Available
Hyperreflexia17.02.01.002--Not Available
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypertonia17.05.02.001; 15.05.04.007--Not Available
Hyperventilation22.02.01.006; 19.01.02.004--Not Available
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypochromic anaemia01.03.02.004--Not Available
Hypoglycaemia14.06.03.001; 05.06.03.001--
Hypokalaemia14.05.03.002--
Hypokinesia17.01.02.009--Not Available
Hyponatraemia14.05.04.002--
Hyporeflexia17.02.01.003--
Hypotension24.06.03.002--
Hypothermia12.05.03.001; 08.05.01.003--
Hypothyroidism14.11.01.012; 05.02.03.001--
Increased appetite14.03.01.003; 08.01.09.027--Not Available
Infection11.01.08.002--Not Available
Infection parasitic11.01.08.003--Not Available
Influenza like illness08.01.03.010--
Injury12.01.08.004--Not Available
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