Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status approved
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 33342-088; 71335-1352; 62938-0020; 65977-0067; 33342-087; 63850-7138; 63850-7119
UNII 51086HBW8G
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal distension07.01.04.001--
Abdominal pain07.01.05.0020.000805%
Abdominal pain upper07.01.05.0030.000668%
Abortion18.01.01.0010.000136%Not Available
Aggression19.05.01.0010.000136%Not Available
Agitation17.02.05.012; 19.06.02.0010.000546%
Akinesia17.01.02.003--Not Available
Anaphylactic shock24.06.02.004; 10.01.07.002--Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Angina pectoris24.04.04.002; 02.02.02.0020.000136%
Angioedema22.04.02.008; 23.04.01.001; 10.01.05.009--Not Available
Anxiety19.06.02.0020.000737%
Arrhythmia02.03.02.001--Not Available
Arteriospasm coronary12.02.01.031; 24.04.04.005; 02.02.02.005--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Ataxia17.02.02.001; 08.01.02.004--
Aura17.02.07.011--Not Available
Blindness unilateral06.02.10.007; 17.17.01.016--Not Available
Blood pressure increased13.14.03.005--Not Available
Body temperature increased13.15.01.001--Not Available
Bradycardia02.03.02.002--Not Available
Bradykinesia17.01.02.004--Not Available
Cerebral infarction24.04.06.002; 17.08.01.0040.000136%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.007--
Chest discomfort22.12.02.002; 08.01.08.019; 02.02.02.0090.000709%Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.0110.000846%Not Available
Chills15.05.03.016; 08.01.09.0010.000436%
Colitis ischaemic24.04.08.012; 07.08.01.0040.000436%Not Available
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