Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Rizatriptan
Drug ID BADD_D01957
Description Rizatriptan is a triptan drug used for the treatment of migraine headaches. It is a selective 5-hydroxytryptamine1 receptor subtype agonist.
Indications and Usage For treatment of acute migraine attacks with or without aura.
Marketing Status approved
ATC Code N02CC04
DrugBank ID DB00953
KEGG ID D08485
MeSH ID C093622
PubChem ID 5078
TTD Drug ID D0S9MU
NDC Product Code 33342-088; 71335-1352; 62938-0020; 65977-0067; 33342-087; 63850-7138; 63850-7119
UNII 51086HBW8G
Synonyms rizatriptan | N,N-dimethyl-2-(5-(1,2,4-triazol-1-ylmethyl)-1H-indole-3-yl)ethylamine | rizatriptan benzoate | MK 0462 | MK-0462 | MK-462 | MK 462 | L 705,126 | L-705,126 | L-705126 | L 705126 | Maxalt
Chemical Information
Molecular Formula C15H19N5
CAS Registry Number 144034-80-0
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vision blurred17.17.01.010; 06.02.06.0070.000368%
Visual impairment06.02.10.0130.000696%Not Available
Vomiting07.01.07.0030.003273%
Wheezing22.03.01.009--
Yawning22.12.03.037--Not Available
Coronary artery dissection02.02.01.004; 12.02.01.035; 24.02.02.0010.000205%Not Available
Hypoacusis04.02.01.006--
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Eye pruritus06.04.05.006--Not Available
Musculoskeletal stiffness15.03.05.0270.000205%Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Temperature intolerance08.01.09.022--Not Available
Urine output increased13.13.03.002--Not Available
Hot flush24.03.01.005; 21.02.02.001; 08.01.03.027--
Adverse event08.06.01.0100.000668%Not Available
Ischaemia24.04.02.004--Not Available
Ischaemic stroke17.08.01.018; 24.04.06.0100.000136%Not Available
Mental disorder19.07.01.002--Not Available
Cardiac valve disease02.07.02.0010.000273%Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Inner ear disorder04.04.02.002--Not Available
Adverse drug reaction08.06.01.0090.000464%Not Available
Drug intolerance08.06.01.0130.000696%Not Available
Sinus disorder22.04.06.002--
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.000341%Not Available
Treatment failure08.06.01.0170.000764%Not Available
Regurgitation07.01.07.004--Not Available
Drug-induced liver injury12.03.01.044; 09.01.07.0230.000136%Not Available
Medication overuse headache17.14.01.015; 08.06.02.015--Not Available
Reversible cerebral vasoconstriction syndrome18.06.01.004; 17.08.02.014; 24.04.06.0260.000477%Not Available
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