Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ropivacaine hydrochloride monohydrate
Drug ID BADD_D01969
Description Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.
Indications and Usage Used in obstetric anesthesia and regional anesthesia for surgery.
Marketing Status approved
ATC Code N01BB09
DrugBank ID DB00296
KEGG ID D08490; D04048
MeSH ID D000077212
PubChem ID 6918111
TTD Drug ID D09RHQ
NDC Product Code 72375-0004; 66583-0610
UNII V910P86109
Synonyms Ropivacaine | 1-Propyl-2',6'-pipecoloxylidide | 1 Propyl 2',6' pipecoloxylidide | Naropin | Ropivacaine Monohydrochloride | Ropivacaine Hydrochloride | AL 381 | AL-381 | AL381 | Naropeine | LEA 103 | LEA-103 | LEA103 | Ropivacaine Monohydrochloride, (S)-isomer
Chemical Information
Molecular Formula C17H29ClN2O2
CAS Registry Number 132112-35-7
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Accident12.01.08.001--Not Available
Acoustic stimulation tests abnormal13.07.08.001--Not Available
Agitation17.02.05.012; 19.06.02.001--
Amnesia19.20.01.001; 17.03.02.001--
Anaemia01.03.02.001--
Anxiety19.06.02.002--
Apgar score low13.15.01.012--Not Available
Arrhythmia02.03.02.001--Not Available
Asthenia08.01.01.001--Not Available
Atrial fibrillation02.03.03.002--
Back pain15.03.04.005--
Bradycardia02.03.02.002--Not Available
Bradycardia foetal18.03.02.006; 02.03.02.018--Not Available
Breast feeding26.05.01.001--Not Available
Bronchospasm22.03.01.004; 10.01.03.012--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chills15.05.03.016; 08.01.09.001--
Coma17.02.09.001--Not Available
Confusional state17.02.03.005; 19.13.01.001--
Cough22.02.03.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyskinesia17.01.02.006--
Dyspnoea22.02.01.004; 02.11.05.003--
Electrocardiogram abnormal13.14.05.001--Not Available
Electrocardiogram ST segment abnormal13.14.05.017--Not Available
Extrasystoles02.03.02.003--Not Available
Eyelid ptosis17.17.02.004; 06.05.01.002--Not Available
Failed trial of labour18.07.03.002--Not Available
Fever neonatal08.05.02.007; 18.04.01.009--Not Available
Foetal distress syndrome18.03.02.003--Not Available
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