Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ropivacaine hydrochloride monohydrate
Drug ID BADD_D01969
Description Ropivacaine is an aminoamide local anaesthetic drug commonly marketed by AstraZeneca under the trade name Naropin. It is present as a racemic mixture of the enantiomers containing equal proportions of the “S” and “R” forms. The marketed form contains the single S-enantiomer as the active ingredient.
Indications and Usage Used in obstetric anesthesia and regional anesthesia for surgery.
Marketing Status approved
ATC Code N01BB09
DrugBank ID DB00296
KEGG ID D08490; D04048
MeSH ID D000077212
PubChem ID 6918111
TTD Drug ID D09RHQ
NDC Product Code 72375-0004; 66583-0610
UNII V910P86109
Synonyms Ropivacaine | 1-Propyl-2',6'-pipecoloxylidide | 1 Propyl 2',6' pipecoloxylidide | Naropin | Ropivacaine Monohydrochloride | Ropivacaine Hydrochloride | AL 381 | AL-381 | AL381 | Naropeine | LEA 103 | LEA-103 | LEA103 | Ropivacaine Monohydrochloride, (S)-isomer
Chemical Information
Molecular Formula C17H29ClN2O2
CAS Registry Number 132112-35-7
SMILES CCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hallucination19.10.04.003--
Headache17.14.01.001--
Hepatomegaly09.01.05.001--Not Available
Horner's syndrome17.05.01.004; 16.32.03.006; 06.09.04.002--Not Available
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypoglycaemia neonatal05.06.03.006; 14.06.03.006; 18.04.06.003--Not Available
Hypokalaemia14.05.03.002--
Hypokinesia17.01.02.009--Not Available
Hypomagnesaemia14.04.02.001--
Hypotension24.06.03.002--
Hypothermia12.05.03.001; 08.05.01.003--
Hypotonia15.05.04.008; 17.05.02.002--Not Available
Injection site pain12.07.03.011; 08.02.03.010--Not Available
Injury12.01.08.004--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Jaundice neonatal18.04.08.001; 09.01.01.008; 01.06.04.006--Not Available
Malaise08.01.01.003--
Micturition disorder20.02.02.005--Not Available
Muscle spasms15.05.03.004--
Myalgia15.05.02.001--
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Nightmare19.02.03.003--Not Available
Oliguria20.01.03.004--Not Available
Orthostatic hypotension24.06.03.004; 17.05.01.020--Not Available
Pain08.01.08.004--
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