| Pharmaceutical Information |
| Drug Name |
Roxithromycin |
| Drug ID |
BADD_D01975 |
| Description |
Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to [erythromycin], [azithromycin], or [clarithromycin]. It was shown to be more effective against certain Gram-negative bacteria, particularly _Legionella pneumophila_. Roxithromycin exerts its antibacterial action by binding to the bacterial ribosome and interfering with bacterial protein synthesis. It is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. |
| Indications and Usage |
Used to treat respiratory tract, urinary and soft tissue infections. |
| Marketing Status |
approved; investigational; withdrawn |
| ATC Code |
J01FA06 |
| DrugBank ID |
DB00778
|
| KEGG ID |
D01710
|
| MeSH ID |
D015575
|
| PubChem ID |
444037
|
| TTD Drug ID |
D0Y4FL
|
| NDC Product Code |
Not Available |
| UNII |
21KOF230FA
|
| Synonyms |
Roxithromycin | Rulide | Infectoroxit | Rulid | Macrosil | MTW-Roxithromycin | Rotesan | Rotramin | Roxi 1A Pharma | Roxi-paed 1A Pharma | Roxi Basics | Roxi TAD | roxi von ct | Roxi-Puren | Roxi-Q | Roxi-saar | Roxi-Wolff | Roxibeta | roxidura | Roxigamma | Roxigrün | Roxihexal | Roxithro-Lich | RU 28965 | RU-28965 | RU28965 | RU 965 | RU-965 | RU965 | Biaxsig | Claramid |
|
| Chemical Information |
| Molecular Formula |
C41H76N2O15 |
| CAS Registry Number |
80214-83-1 |
| SMILES |
CCC1C(C(C(C(=NOCOCCOC)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(
O3)C)N(C)C)O)(C)O)C)C)O)(C)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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