Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Sargramostim
Drug ID BADD_D01990
Description Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.
Indications and Usage For the treatment of cancer and bone marrow transplant
Marketing Status approved; investigational
ATC Code L03AA09
DrugBank ID DB00020
KEGG ID D05803
MeSH ID C081222
PubChem ID Not Available
TTD Drug ID D0XT5Y
NDC Product Code 71837-5843
UNII 5TAA004E22
Synonyms sargramostim | 23-L-leucine-colony-stimulating factor 2 (human clone pHG25 protein moiety) | Leukine | Prokine
Chemical Information
Molecular Formula Not Available
CAS Registry Number 123774-72-1
SMILES Not Available
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Haematemesis24.07.02.011; 07.12.02.002--Not Available
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Headache17.14.01.001--
Hepatomegaly09.01.05.001--Not Available
Hyperbilirubinaemia14.11.01.010; 09.01.01.003; 01.06.04.003--Not Available
Hyperglycaemia14.06.02.002; 05.06.02.002--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypersensitivity10.01.03.003--
Hypertension24.08.02.001--
Hypomagnesaemia14.04.02.001--
Hypotension24.06.03.002--
Infection11.01.08.002--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Leukopenia01.02.02.001--Not Available
Lung disorder22.02.07.001--Not Available
Malaise08.01.01.003--
Motor neurone disease17.05.05.002--Not Available
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Pericardial effusion02.06.01.002--
Petechiae23.06.01.003; 24.07.06.004; 01.01.03.002--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
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