Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Semaxanib
Drug ID BADD_D02007
Description Not Available
Indications and Usage Investigated for use/treatment in colorectal cancer and lung cancer.
Marketing Status investigational
ATC Code Not Available
DrugBank ID DB06436
KEGG ID D05819
MeSH ID C116890
PubChem ID 5329098
TTD Drug ID Not Available
NDC Product Code Not Available
UNII 71IA9S35AJ
Synonyms Semaxinib | SU 5416 | SU5416 | Sugen 5416 | SU-5416 | 3-(2,4-dimethylpyrrol-5-yl)methylidene-indolin-2-one
Chemical Information
Molecular Formula C15H14N2O
CAS Registry Number 194413-58-6
SMILES CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Oedema peripheral08.01.07.007; 02.05.04.007; 14.05.06.011--
Optic neuritis10.02.01.097; 17.04.05.001; 06.04.08.002--Not Available
Pain08.01.08.004--
Pain in extremity15.03.04.010--
Painful respiration22.12.02.011--Not Available
Palpitations02.11.04.012--
Pancytopenia01.03.03.003--Not Available
Papilloedema17.07.02.004; 24.03.07.001; 06.09.02.002--
Paraesthesia23.03.03.094; 17.02.06.005--
Peripheral ischaemia24.04.03.002--
Phlebitis12.02.01.002; 24.12.03.004--
Photosensitivity reaction23.03.09.003--
Plasma cell myeloma16.23.02.004; 01.14.02.004--Not Available
Plasmacytoma16.23.02.002; 01.14.02.002--Not Available
Platelet count abnormal13.01.04.005--Not Available
Portal vein thrombosis24.01.03.003; 09.01.06.007--
Prurigo23.03.04.017--Not Available
Pruritus23.03.12.001--
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash papular23.03.13.017--Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.001--
Rhinorrhoea22.12.03.021--
Skin disorder23.03.03.007--Not Available
Skin odour abnormal23.03.03.012--
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