| Pharmaceutical Information |
| Drug Name |
Sodium fluoride |
| Drug ID |
BADD_D02039 |
| Description |
Sodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].[L4894] Sodium fluoride's benefits on dental health were first observed in the 1930s, when individuals in communities with fluoridated drinking water showed less tooth decay than those without fluoridated water. The use of fluoride in dental practice began in the 1940s. Now, sodium fluoride may be found in a variety of gels, varnishes, rinses, toothpaste products, and fluoride treatments provided in dental care.[A181670,A181688] According to the American Dental Association (ADA), thorough evidence reviews have indicated that the use of fluoride to prevent and control dental caries is safe when used correctly and is highly effective in reducing the prevalence of caries.[L7691] |
| Indications and Usage |
Sodium fluoride in the oral or topical form is indicated for the prevention and control of dental caries and for the maintenance of dental health.[A181652,L7670] Fluoride supplements in the form of tablets and other formulas may be prescribed to prevent tooth decay in high-risk children aged 6 months to 16 years old whose drinking water source contains low fluoride concentrations.[L7691] |
| Marketing Status |
approved |
| ATC Code |
A01AA01; A12CD01 |
| DrugBank ID |
DB09325
|
| KEGG ID |
D00943
|
| MeSH ID |
D012969
|
| PubChem ID |
5235
|
| TTD Drug ID |
D02IUD
|
| NDC Product Code |
72805-130; 0699-0152; 74724-0020; 75065-001; 75065-004; 75065-007; 79903-033; 0869-0163; 0869-0482; 49452-6740; 10056-530; 10237-786; 11527-044; 11527-045; 11527-750; 11822-4004; 11822-9718; 24794-107; 24794-108; 25047-764; 25047-765; 25047-771; 25047-773; 25047-775; 30142-482; 35000-190; 35000-198; 35000-743; 35000-930; 35000-969; 35000-988; 35000-993; 35000-996; 36800-482; 37000-171; 37000-208; 37000-212; 37000-214; 37000-839; 37000-853; 37000-924; 37000-952; 37000-962; 37012-163; 0126-0286; 37808-576; 0135-0234; 41163-004; 41167-0922; 41167-0953; 41250-004; 41250-576; 42756-1115; 43136-802; 43136-902; 43498-103; 43498-104; 43498-105; 48878-3130; 53045-204; 53045-252; 53045-266; 53942-004; 53942-213; 0273-0370; 58578-0749; 61041-212; 61578-217; 62007-052; 62007-802; 62007-805; 62007-810; 63629-1133; 64778-0216; 64854-018; 64980-307; 65517-2018; 65954-064; 66467-2230; 66467-2240; 67933-0016; 68400-120; 68400-701; 68400-704; 68987-011; 69301-031; 69423-751; 69423-770; 69423-773; 69423-887; 69423-894; 69423-910; 69423-913; 69423-933; 69423-947; 69484-050; 69509-052; 69509-054; 69842-429; 69968-0497; 69968-0690; 70108-005; 70737-016; 72288-004; 72299-011; 72299-016; 72299-020; 75065-021; 77573-012; 14639-6441; 10056-415; 10237-633; 10237-635; 10237-653; 10237-666; 30142-563; 35000-205; 35000-229; 35000-261; 35000-734; 35000-744; 35000-900; 35000-937; 35000-953; 35000-972; 35573-435; 37000-025; 37000-028; 37000-494; 37000-862; 37000-932; 37000-956; 37000-961; 37000-993; 37012-482; 0126-0289; 37808-435; 41163-213; 0135-0558; 41167-0940; 41250-213; 43498-102; 48878-3150; 51009-149; 51009-840; 51009-915; 51824-046; 53045-200; 53045-203; 53045-268; 55316-213; 55882-6118; 55882-6210; 0273-0241; 0273-0393; 57660-003; 61649-731; 62007-053; 62007-055; 62007-100; 62007-126; 62007-316; 62007-820; 62007-825; 62007-826; 0363-0482; 63783-501; 63940-163; 64778-0446; 66467-2270; 67239-0226; 67777-175; 68400-135; 69301-025; 69301-032; 69367-309; 69423-792; 69423-882; 69423-907; 69423-949; 69423-961; 69509-055; 69509-058; 69842-548; 69968-0697; 70605-039; 70766-007; 71141-174; 72288-439; 72288-576; 72299-017; 72551-251; 72655-300; 74690-008; 77935-303; 79481-0201; 81740-002; 82149-001; 82500-010; 83367-102; 86157-0006; 86157-0012; 10237-652; 10237-675; 10237-785; 10237-794; 10237-795; 11822-5927; 24794-105; 35000-127; 35000-195; 35000-199; 35000-233; 35000-264; 35000-418; 35000-742; 35000-902; 35000-924; 37000-022; 37000-167; 37000-469; 37000-511; 37000-925; 37000-943; 37000-958; 37000-968; 37012-004; 0126-0033; 37808-320; 37808-808; 41163-581; 41167-0965; 41250-531; 42291-741; 43136-602; 43136-820; 43136-903; 50268-733; 50594-971; 51206-310; 53045-206; 53045-207; 55301-163; 55315-163; 55873-002; 0273-0345; 0273-0358; 58578-1234; 58657-160; 59883-718; 59883-821; 61041-211; 61995-0601; 62007-307; 62007-829; 63783-400; 65222-411; 65954-041; 0404-1701; 0404-1721; 66923-007; 68400-121; 69367-310; 69367-311; 69423-769; 69423-850; 69423-881; 69423-889; 69423-924; 69423-928; 69509-053; 69509-059; 69745-014; 69842-581; 69968-0537; 69968-0606; 70683-0703; 72135-005; 72299-010; 72299-023; 72476-482; 72551-246; 53942-435; 53942-581; 54473-300; 55316-435; 55882-6116; 56062-163; 0273-0341; 0273-0346; 58578-0517; 58578-0759; 58657-162; 58933-470; 58933-879; 59088-106; 59779-163; 59779-482; 59883-820; 0363-0014 |
| UNII |
8ZYQ1474W7
|
| Synonyms |
Sodium Fluoride | Fluoride, Sodium | Fluorides, Sodium | Sodium Fluorides | Zymafluor | Zymafluors | Fluoristat | Fluoristats | Ossin | Ossins |
|
| Chemical Information |
| Molecular Formula |
NaF |
| CAS Registry Number |
7681-49-4 |
| SMILES |
[F-].[Na+] |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
