Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sodium polystyrene sulfonate
Drug ID BADD_D02049
Description Sodium polystyrene sulfonate is a medication used to treat abnormally high potassium levels. It may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Indications and Usage Used to treat abnormally high potassium levels.
Marketing Status approved; investigational
ATC Code V03AE01
DrugBank ID DB01344
KEGG ID D03263
MeSH ID C003321
PubChem ID 75905
TTD Drug ID Not Available
NDC Product Code 10702-036; 68444-0002; 46287-006; 53933-7246; 55363-254; 68444-0004; 68444-0005; 62135-340; 63629-8849; 42806-013; 62250-660; 24658-760; 63629-2390; 11534-166; 68444-0007; 51293-831; 63629-2031; 63629-8850; 68444-0006; 17856-0024; 10135-146; 46287-012; 55154-7353
UNII 1699G8679Z
Synonyms polystyrene sulfonic acid | Kalimate | Kayexalate | poly(styrenesulfonate) | polystyrene sulfonic acid, homopolymer, calcium salt | calcium polystyrene sulfonate | polystyrene sulfonic acid, homopolymer, sodium salt | poly(styrene sulfonate sodium salt) | sodium polystyrene sulfonate | Resonium-A | calcium resonium | polystyrene sulfonate | PSSO3
Chemical Information
Molecular Formula C8H8O3S
CAS Registry Number 98-70-4
SMILES C=CC1=CC=C(C=C1)S(=O)(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bezoar07.11.01.008--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Colitis ischaemic07.08.01.004; 24.04.08.012--Not Available
Constipation07.02.02.001--
Diarrhoea07.02.01.001--
Gastrointestinal necrosis24.04.08.006; 07.15.01.003--
Hypocalcaemia14.04.01.004--
Hypokalaemia14.05.03.002--
Hypomagnesaemia14.04.02.001--
Intestinal obstruction07.13.01.002--Not Available
Nausea07.01.07.001--
Necrosis24.04.02.006; 08.03.03.001--Not Available
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Sodium retention14.05.04.003--Not Available
Vomiting07.01.07.003--
Faecaloma07.01.03.004--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Gastrointestinal ulcer07.04.04.002--Not Available
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