Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Sulfadiazine
Drug ID BADD_D02090
Description One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
Indications and Usage For the treatment of rheumatic fever and meningococcal meningitis
Marketing Status approved; investigational; vet_approved
ATC Code J01EC02
DrugBank ID DB00359
KEGG ID D00587
MeSH ID D013411
PubChem ID 5215
TTD Drug ID D05LKP
NDC Product Code 42806-757; 0185-0757; 38779-3224; 86129-0001; 62705-0229; 63422-703; 76003-1055; 62705-0230; 71236-0003
UNII 0N7609K889
Synonyms Sulfadiazine | Sulphadiazine | Zinc Sulfadiazine | Sulfadiazine, Zinc | Sulfazin | Sulfazine
Chemical Information
Molecular Formula C10H10N4O2S
CAS Registry Number 68-35-9
SMILES C1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Urticaria23.04.02.001; 10.01.06.001--
Vascular purpura24.07.06.011; 23.06.01.008; 01.01.04.007--Not Available
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.003--
Tubulointerstitial nephritis20.05.02.002--Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Scleral hyperaemia06.04.07.003--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Scleral disorder06.09.06.002--
Blood disorder01.05.01.004--Not Available
Muscle contracture15.03.05.024--Not Available
Partner stress26.04.01.002--Not Available
Hypersensitivity myocarditis10.01.03.055; 02.04.03.006--Not Available
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