Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Suprofen
Drug ID BADD_D02102
Description An ibuprofen-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic. It is no longer approved for use in the United States.
Indications and Usage Used as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.
Marketing Status approved; withdrawn
ATC Code M01AE07
DrugBank ID DB00870
KEGG ID D00452
MeSH ID D013496
PubChem ID 5359
TTD Drug ID D07BPS
NDC Product Code Not Available
UNII 988GU2F9PE
Synonyms Suprofen | TN-762 | TN 762 | TN762 | R-25061 | R 25061 | R25061
Chemical Information
Molecular Formula C14H12O3S
CAS Registry Number 40828-46-4
SMILES CC(C1=CC=C(C=C1)C(=O)C2=CC=CS2)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Conjunctival oedema06.04.01.001--Not Available
Discomfort08.01.08.003--Not Available
Erythema23.03.06.001--Not Available
Haemoglobin13.01.05.018--Not Available
Haemorrhagic disorder24.07.01.021; 01.01.03.004--Not Available
Hypersensitivity10.01.03.003--
Iritis10.02.01.022; 06.04.03.002--Not Available
Pain08.01.08.004--
Photophobia17.17.02.006; 06.01.01.004--
Pruritus23.03.12.001--
Punctate keratitis06.04.02.003--Not Available
Skin irritation23.03.04.009--Not Available
Haemorrhage24.07.01.002--Not Available
Haemorrhagic diathesis24.07.01.020; 01.01.03.003--Not Available
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