| Pharmaceutical Information |
| Drug Name |
Tacrine hydrochloride |
| Drug ID |
BADD_D02104 |
| Description |
A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous system disorders. Tacrine has been discontinued for the United States market. |
| Indications and Usage |
For the palliative treatment of mild to moderate dementia of the Alzheimer's type. |
| Marketing Status |
approved; investigational; withdrawn |
| ATC Code |
N06DA01 |
| DrugBank ID |
DB00382
|
| KEGG ID |
D02068
|
| MeSH ID |
D013619
|
| PubChem ID |
2723754
|
| TTD Drug ID |
D0E6YQ
|
| NDC Product Code |
Not Available |
| UNII |
4966RNG0BU
|
| Synonyms |
Tacrine | 9-Amino-1,2,3,4-Tetrahydroacridine | 1,2,3,4-Tetrahydro-9-acridinamine | Tetrahydroaminoacridine | 1,2,3,4-Tetrahydroaminoacridine | Romotal | Tenakrin | THA | Cognex | Tacrine Hydrochloride |
|
| Chemical Information |
| Molecular Formula |
C13H15ClN2 |
| CAS Registry Number |
1684-40-8 |
| SMILES |
C1CCC2=NC3=CC=CC=C3C(=C2C1)N.Cl |
| Chemical Structure |
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| ADRs Induced by Drug |
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