| Drug Name |
Technetium tc-99m sestamibi |
| Drug ID |
BADD_D02132 |
| Description |
Technetium Tc-99m sestamibi (commonly sestamibi) is a pharmaceutical agent used in nuclear medicine imaging. The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six methoxyisobutylisonitrile (MIBI) ligands, hence the name sesta (6) MIBI.. Following intravenous injection of the drug, Technetium Tc-99m sestamibi is taken up by the myocardium, parathyroid, and/or breast tissue. The mechanism by which sestamibi localizes to these tissues has not been established. Single photon emission computed tomography (SPECT) is then performed to detect the gamma ray emmitted by the decay of Technetium-99m to Technetium-99.
Currently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects); and 2) evaluating myocardial function and developing information for use in patient management decisions. |
| Indications and Usage |
Technetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and infarction (non-reversible defects); and 2) evaluating myocardial function and developing information for use in patient management decisions. |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB09161
|
| KEGG ID |
D01060; D08763
|
| MeSH ID |
D017256
|
| PubChem ID |
5384
|
| TTD Drug ID |
D0J1TU
|
| NDC Product Code |
45567-0555 |
| UNII |
971Z4W1S09
|
| Synonyms |
Technetium Tc 99m Sestamibi | Tc-99m-Methoxy-2-isobutylisonitrile | Tc 99m Methoxy 2 isobutylisonitrile | Technetium-99m-Hexamibi | Technetium 99m Hexamibi | Tc MIBI | 99mTc-Hexamibi | 99mTc Hexamibi | 99mTc-Sestamibi | 99mTc Sestamibi | Technetium Tc 99m 2-Methoxy-2-methylpropylisonitrile | Technetium Tc 99m 2 Methoxy 2 methylpropylisonitrile | Technetium-99m-Sestamibi | Technetium 99m Sestamibi | Cardiolite | Technetium Tc 99m Sestamibi Chloride |
