| Drug Name |
Telmisartan |
| Drug ID |
BADD_D02147 |
| Description |
Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects. |
| Indications and Usage |
Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors). |
| Marketing Status |
approved; investigational |
| ATC Code |
C09CA07 |
| DrugBank ID |
DB00966
|
| KEGG ID |
D00627
|
| MeSH ID |
D000077333
|
| PubChem ID |
65999
|
| TTD Drug ID |
D0N6RF
|
| NDC Product Code |
72606-506; 10695-139; 65841-805; 68462-199; 68462-200; 72606-507; 55111-095; 62135-536; 62135-537; 62332-089; 65162-293; 71209-049; 52286-0024; 53104-7624; 65404-007; 42291-792; 42571-226; 62135-535; 62332-087; 0597-0041; 72241-017; 65841-804; 65862-868; 68071-2591; 72241-015; 72241-016; 65372-1146; 42291-790; 46708-608; 53002-1794; 71335-1428; 71335-2173; 12666-0010; 50370-0015; 64220-124; 65862-727; 68554-0049; 42571-227; 43547-284; 43547-285; 53746-291; 63629-5682; 0378-2920; 67877-482; 68382-472; 68382-473; 70518-3556; 0597-0039; 65404-006; 66039-895; 71052-679; 45865-836; 53746-292; 65841-806; 65862-867; 68071-5178; 71335-1723; 57451-1206; 46708-610; 67877-483; 68788-8440; 68788-8441; 70518-3300; 0597-0040; 62512-0040; 64552-4026; 65015-845; 42291-791; 43547-283; 53746-293; 62332-088; 0378-2921; 65862-869; 67877-484; 68462-201; 70518-2572; 71209-050; 71209-051; 72606-508; 52562-009; 72761-021; 42571-228; 46708-609; 50090-5490; 63187-951; 0378-2922; 65162-291; 65162-292; 68382-471; 71335-2191; 62331-032; 64220-171 |
| UNII |
U5SYW473RQ
|
| Synonyms |
Telmisartan | 4'-((1,4'-Dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid | Pritor | BIBR 277 | BIBR-277 | Micardis |
