Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone cypionate
Drug ID BADD_D02171
Description Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Indications and Usage Testosterone cypionate is used in males that present conditions derived from a deficiency or absence of endogenous testosterone. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterized by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumors, trauma or radiation.[L1153]
Marketing Status approved
ATC Code Not Available
DrugBank ID DB13943
KEGG ID D00957
MeSH ID C016131
PubChem ID 441404
TTD Drug ID Not Available
NDC Product Code 60870-0252; 64025-0021; 0009-0086; 0143-9726; 52536-625; 62756-016; 0409-6562; 70700-288; 46439-8736; 62991-3132; 48087-0096; 0143-9659; 69097-536; 69097-802; 70700-289; 0574-0827; 76420-065; 51927-0189; 73774-016; 0591-4128; 38779-0164; 46204-0371; 60722-3016; 47781-911; 62756-015; 69097-537; 0143-9005; 63629-8706; 70700-290; 71225-127; 0009-0027; 47781-910; 63187-647; 63629-8705; 0517-1830; 51927-2706; 65089-0049; 73301-010; 0009-0347; 49803-006; 51552-0104; 63275-9982; 82393-114; 62756-017; 0409-6557; 0574-0820; 71205-289; 22552-0010; 43647-678; 0009-0085; 0009-0417; 50090-4147
UNII M0XW1UBI14
Synonyms testosterone 17 beta-cypionate | testosterone cypionate | testosterone 17 beta-cyclopentanepropionate | testosterone 17 beta-cyclopentylpropionate | Depo-Testosterone | Depo-Testosterone Cypionate | deposteron | Duratest | Testa-C | Testex Elmu | Andronate | Depostomead
Chemical Information
Molecular Formula C27H40O3
CAS Registry Number 58-20-8
SMILES CC12CCC3C(C1CCC2OC(=O)CCC4CCCC4)CCC5=CC(=O)CCC35C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cardiomyopathy02.04.01.0010.002097%Not Available
Cardiovascular disorder24.03.02.009; 02.11.01.0100.008387%Not Available
Cerebral infarction24.04.06.002; 17.08.01.0040.001048%Not Available
Cerebral thrombosis24.01.04.003; 17.08.01.0060.001573%Not Available
Cerebrovascular accident24.03.05.001; 17.08.01.0070.061333%
Chest pain02.02.02.011; 22.12.02.003; 08.01.08.0020.011533%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.001048%Not Available
Coordination abnormal17.02.02.0040.001048%Not Available
Coronary artery disease24.04.04.006; 02.02.01.0010.006815%Not Available
Coronary artery occlusion12.02.01.036; 24.04.04.013; 02.02.01.0060.002621%Not Available
Coronary artery thrombosis24.01.05.002; 02.02.01.0070.001048%Not Available
Deafness04.02.01.0010.001048%Not Available
Decreased activity19.11.01.002; 08.01.01.0060.001048%Not Available
Dementia19.20.02.001; 17.03.01.0010.001048%Not Available
Depression19.15.01.0010.014783%
Discomfort08.01.08.0030.002307%Not Available
Disturbance in attention17.03.03.001; 19.21.02.0020.002831%
Drug ineffective08.06.01.0060.077479%Not Available
Dysarthria19.19.03.001; 17.02.08.0010.001048%
Dyspnoea02.11.05.003; 22.02.01.0040.016565%
Embolism venous24.01.01.0030.002097%Not Available
Erection increased21.03.01.004; 19.08.04.002--Not Available
Fear19.06.03.0010.002831%Not Available
Feeling hot08.01.09.0090.001573%Not Available
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Gastrooesophageal reflux disease07.02.02.0030.001048%
Gynaecomastia21.05.04.003; 05.05.02.003--
Haemoptysis02.11.04.009; 24.07.01.006; 22.02.03.0040.001048%Not Available
Headache17.14.01.001--
Hemiparesis17.01.04.0010.001573%
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