Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone cypionate
Drug ID BADD_D02171
Description Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Indications and Usage Testosterone cypionate is used in males that present conditions derived from a deficiency or absence of endogenous testosterone. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterized by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumors, trauma or radiation.[L1153]
Marketing Status approved
ATC Code Not Available
DrugBank ID DB13943
KEGG ID D00957
MeSH ID C016131
PubChem ID 441404
TTD Drug ID Not Available
NDC Product Code 60870-0252; 64025-0021; 0009-0086; 0143-9726; 52536-625; 62756-016; 0409-6562; 70700-288; 46439-8736; 62991-3132; 48087-0096; 0143-9659; 69097-536; 69097-802; 70700-289; 0574-0827; 76420-065; 51927-0189; 73774-016; 0591-4128; 38779-0164; 46204-0371; 60722-3016; 47781-911; 62756-015; 69097-537; 0143-9005; 63629-8706; 70700-290; 71225-127; 0009-0027; 47781-910; 63187-647; 63629-8705; 0517-1830; 51927-2706; 65089-0049; 73301-010; 0009-0347; 49803-006; 51552-0104; 63275-9982; 82393-114; 62756-017; 0409-6557; 0574-0820; 71205-289; 22552-0010; 43647-678; 0009-0085; 0009-0417; 50090-4147
UNII M0XW1UBI14
Synonyms testosterone 17 beta-cypionate | testosterone cypionate | testosterone 17 beta-cyclopentanepropionate | testosterone 17 beta-cyclopentylpropionate | Depo-Testosterone | Depo-Testosterone Cypionate | deposteron | Duratest | Testa-C | Testex Elmu | Andronate | Depostomead
Chemical Information
Molecular Formula C27H40O3
CAS Registry Number 58-20-8
SMILES CC12CCC3C(C1CCC2OC(=O)CCC4CCCC4)CCC5=CC(=O)CCC35C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Breast disorder21.05.04.0040.001573%Not Available
Cardiac disorder02.11.01.0030.018872%Not Available
Libido disorder21.03.02.006; 19.08.03.004--Not Available
Ischaemic stroke24.04.06.010; 17.08.01.0180.006291%Not Available
Motor dysfunction17.01.02.031; 15.05.06.0060.001048%Not Available
Cardiac valve disease02.07.02.0010.001048%Not Available
Erectile dysfunction21.03.01.007; 19.08.04.0010.002097%
Arterial occlusive disease24.04.02.0210.001048%Not Available
Brain injury17.11.01.003; 19.07.03.0070.005242%Not Available
Androgenetic alopecia23.02.02.002; 05.05.04.001--Not Available
Frustration tolerance decreased19.04.02.0160.001048%Not Available
Post-traumatic stress disorder19.06.06.0020.002621%Not Available
Cardiac ventricular thrombosis02.11.01.008; 24.01.05.0060.001048%Not Available
Drug ineffective for unapproved indication12.09.02.002; 08.06.01.0380.002307%Not Available
Gait inability08.01.02.011; 17.02.05.0690.001048%Not Available
Idiopathic intracranial hypertension17.07.02.0110.011533%Not Available
Superficial vein thrombosis24.01.02.0160.002097%Not Available
Therapeutic product effect decreased08.06.01.0500.007129%Not Available
Therapeutic product effect incomplete08.06.01.0520.005347%Not Available
Therapeutic product effect increased08.06.01.0530.003565%Not Available
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