Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Testosterone cypionate
Drug ID BADD_D02171
Description Testosterone cypionate is a synthetic derivative of testosterone in the form of an oil-soluble 17 (beta)-cyclopentylpropionate ester. Its benefit compared to other testosterone derivatives is the slow rate of release after injection and longer half-life. It was developed by the company Pharmacia and Upjohn and FDA approved on July 25, 1979.
Indications and Usage Testosterone cypionate is used in males that present conditions derived from a deficiency or absence of endogenous testosterone. These conditions are 1) primary hypogonadism, defined as the testicular failure due to cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome or orchidectomy; and 2) hypogonadotropic hypogonadism characterized by idiopathic gonadotropin, LHRH deficiency or pituitary-hypothalamic injury from tumors, trauma or radiation.[L1153]
Marketing Status approved
ATC Code Not Available
DrugBank ID DB13943
KEGG ID D00957
MeSH ID C016131
PubChem ID 441404
TTD Drug ID Not Available
NDC Product Code 60870-0252; 64025-0021; 0009-0086; 0143-9726; 52536-625; 62756-016; 0409-6562; 70700-288; 46439-8736; 62991-3132; 48087-0096; 0143-9659; 69097-536; 69097-802; 70700-289; 0574-0827; 76420-065; 51927-0189; 73774-016; 0591-4128; 38779-0164; 46204-0371; 60722-3016; 47781-911; 62756-015; 69097-537; 0143-9005; 63629-8706; 70700-290; 71225-127; 0009-0027; 47781-910; 63187-647; 63629-8705; 0517-1830; 51927-2706; 65089-0049; 73301-010; 0009-0347; 49803-006; 51552-0104; 63275-9982; 82393-114; 62756-017; 0409-6557; 0574-0820; 71205-289; 22552-0010; 43647-678; 0009-0085; 0009-0417; 50090-4147
UNII M0XW1UBI14
Synonyms testosterone 17 beta-cypionate | testosterone cypionate | testosterone 17 beta-cyclopentanepropionate | testosterone 17 beta-cyclopentylpropionate | Depo-Testosterone | Depo-Testosterone Cypionate | deposteron | Duratest | Testa-C | Testex Elmu | Andronate | Depostomead
Chemical Information
Molecular Formula C27H40O3
CAS Registry Number 58-20-8
SMILES CC12CCC3C(C1CCC2OC(=O)CCC4CCCC4)CCC5=CC(=O)CCC35C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acne23.02.01.0010.008912%Not Available
Acute myocardial infarction24.04.04.001; 02.02.02.0010.018872%Not Available
Amnesia19.20.01.001; 17.03.02.0010.003145%
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Anger19.04.02.0010.001573%Not Available
Angina pectoris24.04.04.002; 02.02.02.0020.003669%
Angina unstable24.04.04.004; 02.02.02.0040.001048%Not Available
Anxiety19.06.02.0020.011113%
Aphasia19.21.01.001; 17.02.03.0010.001048%
Arrhythmia02.03.02.0010.001048%Not Available
Arteriosclerosis coronary artery24.04.04.012; 02.02.01.0110.001048%Not Available
Arthropathy15.01.01.0030.002307%Not Available
Asthenia08.01.01.0010.009855%Not Available
Atrial fibrillation02.03.03.0020.004718%
Atrial flutter02.03.03.0030.001573%
Azoospermia21.03.03.001--
Blindness06.02.10.003; 17.17.01.0030.003145%Not Available
Blindness unilateral06.02.10.007; 17.17.01.0160.001573%Not Available
Blood calcium13.11.01.041--Not Available
Blood calcium decreased13.11.01.002--Not Available
Blood chloride13.11.01.042--Not Available
Blood phosphorus13.11.01.023--Not Available
Blood potassium13.11.01.032--Not Available
Blood potassium abnormal13.11.01.024--Not Available
Burning sensation17.02.06.001; 08.01.09.0290.014783%Not Available
Cardiac arrest02.03.04.0010.006815%
Cardiac failure02.05.01.0010.002097%
Cardiac failure congestive02.05.01.0020.009960%Not Available
Cardio-respiratory arrest22.02.06.007; 02.03.04.0020.001573%Not Available
Cardiogenic shock24.06.02.006; 02.05.01.0030.001573%Not Available
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