Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Thiabendazole
Drug ID BADD_D02196
Description 2-Substituted benzimidazole first introduced in 1962. It is active against a variety of nematodes and is the drug of choice for strongyloidiasis. It has CNS side effects and hepatototoxic potential. (From Smith and Reynard, Textbook of Pharmacology, 1992, p919)
Indications and Usage For the treatment of strongyloidiasis (threadworm), cutaneous larva migrans (creeping eruption), visceral larva migrans, and trichinosis.
Marketing Status approved; vet_approved
ATC Code Not Available
DrugBank ID DB00730
KEGG ID D00372
MeSH ID D013827
PubChem ID 5430
TTD Drug ID D08QCJ
NDC Product Code 68022-7046; 51927-2278; 59014-0050; 49452-7723
UNII N1Q45E87DT
Synonyms Thiabendazole | Tiabendazol | Thibendole | 2-(4'-Thiazolyl)Benzimidazole | Mintezol | Omnizole | Mintesol
Chemical Information
Molecular Formula C10H7N3S
CAS Registry Number 148-79-8
SMILES C1=CC=C2C(=C1)NC(=N2)C3=CSC=N3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypersensitivity10.01.03.003--
Hypoaesthesia17.02.06.023; 23.03.03.081--Not Available
Hypotension24.06.03.002--
Irritability19.04.02.013; 08.01.03.011--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Leukopenia01.02.02.001--Not Available
Lymphadenopathy01.09.01.002--Not Available
Nausea07.01.07.001--
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Seizure17.12.03.001--
Sensory loss17.02.07.007--Not Available
Sjogren's syndrome07.06.01.010; 06.08.02.011; 15.06.01.015; 10.04.04.009--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Tinnitus17.04.07.004; 04.04.01.002--
Vision blurred17.17.01.010; 06.02.06.007--
Visual acuity reduced06.02.10.012; 17.17.01.011--
Visual impairment06.02.10.013--Not Available
Vomiting07.01.07.003--
Xanthopsia06.02.05.002--Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
Urine odour abnormal20.02.01.020--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Liver injury12.01.17.012; 09.01.07.022--Not Available
Mucosal disorder08.01.06.029--Not Available
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