Pharmaceutical Information |
Drug Name |
Thioridazine |
Drug ID |
BADD_D02200 |
Description |
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618).
Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias. |
Indications and Usage |
For the treatment of schizophrenia and generalized anxiety disorder. |
Marketing Status |
approved; withdrawn |
ATC Code |
N05AC02 |
DrugBank ID |
DB00679
|
KEGG ID |
D00373
|
MeSH ID |
D013881
|
PubChem ID |
5452
|
TTD Drug ID |
D0U1OE
|
NDC Product Code |
Not Available |
UNII |
N3D6TG58NI
|
Synonyms |
Thioridazine | Thioridazine Hydrochloride | Thioridazine HCL | Thioridazine-Neurazpharm | Thioridazine Neurazpharm | ThioridazineNeurazpharm | Thiozine | Aldazine | Meleril | Mellaril | Melleril | Melleryl | Melleretten | Melzine | Rideril | Sonapax | Apo-Thioridazine | Apo Thioridazine | ApoThioridazine |
|
Chemical Information |
Molecular Formula |
C21H26N2S2 |
CAS Registry Number |
50-52-2 |
SMILES |
CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC |
Chemical Structure |
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ADRs Induced by Drug |
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