Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tinidazole
Drug ID BADD_D02221
Description A nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica_, and _Giardia lamblia_ infections.
Indications and Usage For the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestinal amebiasis and amebic liver abscess caused by E. histolytica in both adults and pediatric patients older than three years of age.
Marketing Status approved; investigational
ATC Code G01AF21; J01XD02; P01AB02
DrugBank ID DB00911
KEGG ID D01426
MeSH ID D014011
PubChem ID 5479
TTD Drug ID Not Available
NDC Product Code 51927-2391; 43386-550; 43386-551; 64980-426; 38779-2957; 42799-208; 0178-8500; 67296-1836; 14799-2005; 64980-427; 51552-0683; 42799-207; 0178-8250
UNII 033KF7V46H
Synonyms Tinidazole | Tricolam | Fasigyn | Fasigyne | Fasigin | Fasygin | Simplotan | Bioshik | CP-12,574 | CP 12,574 | CP12,574 | CP-12574 | CP 12574 | CP12574
Chemical Information
Molecular Formula C8H13N3O4S
CAS Registry Number 148159-84-6
SMILES CCS(=O)(=O)CCN1C(=NC=C1[N+](=O)[O-])C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Rash23.03.13.001--Not Available
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Sensory loss17.02.07.007--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Stomatitis07.05.06.005--
Thirst14.03.02.007; 08.01.09.021--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tongue discolouration07.14.02.006--Not Available
Upper respiratory tract infection22.07.03.011; 11.01.13.009--
Urethral disorder20.07.01.002--Not Available
Urinary tract disorder20.08.01.001--Not Available
Urinary tract infection20.08.02.001; 11.01.14.004--
Urine abnormality20.02.01.013--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vaginal discharge21.08.02.002--
Vaginal odour21.08.02.008--Not Available
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.003--
Vulvovaginal discomfort21.08.02.005--Not Available
Epigastric discomfort07.01.02.004--Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Transaminases increased13.03.04.036--Not Available
Angiopathy24.03.02.007--Not Available
Malnutrition14.03.02.004--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Ill-defined disorder08.01.03.049--Not Available
Inner ear disorder04.04.02.002--Not Available
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