Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Tolmetin sodium
Drug ID BADD_D02242
Description A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Indications and Usage For the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis, including the treatment of acute flares long-term management. Also for treatment of juvenile rheumatoid arthritis.
Marketing Status approved
ATC Code M01AB03; M02AA21
DrugBank ID DB00500
KEGG ID D00158
MeSH ID D014046
PubChem ID 23665411
TTD Drug ID D09BHB
NDC Product Code 65015-717; 16571-825; 16571-826
UNII 02N1TZF99F
Synonyms Tolmetin | Tolectin | Tolmetin Sodium, Anhydrous | Anhydrous Tolmetin Sodium | Tolmetin Sodium Anhydrous | Anhydrous, Tolmetin Sodium | Sodium Anhydrous, Tolmetin | McN-2559 | McN 2559 | McN2559 | Tolmetin Sodium | Sodium, Tolmetin | Tolmetin Sodium, Dihydrate | Dihydrate Tolmetin Sodium
Chemical Information
Molecular Formula C15H14NNaO3
CAS Registry Number 35711-34-3
SMILES CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)[O-].[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Agranulocytosis01.02.03.001--Not Available
Anaphylactoid reaction10.01.07.003; 24.06.03.007--Not Available
Asthenia08.01.01.001--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood urea increased13.13.01.006--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Constipation07.02.02.001--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyspepsia07.01.02.001--
Dysuria20.02.02.002--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema multiforme23.03.01.003; 10.01.03.015--
Flatulence07.01.04.002--
Gastritis07.08.02.001--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal haemorrhage24.07.02.009; 07.12.02.001--Not Available
Gastrointestinal perforation07.04.04.001--Not Available
Glossitis07.14.01.001--Not Available
Granulocytopenia01.02.03.003--Not Available
Haematocrit decreased13.01.05.001--Not Available
Haematuria20.02.01.006; 21.10.01.018; 24.07.01.047--
Haemoglobin decreased13.01.05.003--Not Available
Haemolytic anaemia01.06.03.002--Not Available
Headache17.14.01.001--
Hepatitis09.01.07.004--Not Available
Liver function test abnormal13.03.04.030--Not Available
Lymphadenopathy01.09.01.002--Not Available
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