| Pharmaceutical Information |
| Drug Name |
Tositumomab |
| Drug ID |
BADD_D02252 |
| Description |
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine). |
| Indications and Usage |
For treatment of non-Hodgkin's lymphoma (CD20 positive, follicular) |
| Marketing Status |
approved; investigational |
| ATC Code |
Not Available |
| DrugBank ID |
DB00081
|
| KEGG ID |
D08621
|
| MeSH ID |
C119496
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
D0I2AV
|
| NDC Product Code |
Not Available |
| UNII |
0343IGH41U
|
| Synonyms |
tositumomab I-131 | 131I-tositumomab | anti-B1 antibody I-131 | tositumomab conjugate with 131I | iodine (131I) tositumomab | iodine-131 tositumomab | I-131 anti-B1 antibody | iodine-131 anti-B1 monoclonal antibody | iodine-131-labeled anti-CD20 antibody | iodine-131-tositumomab | tositumomab iodine-131 | iodine-131 anti-B1 antibody | 131I anti-B1 | Bexxar |
|
| Chemical Information |
| Molecular Formula |
Not Available |
| CAS Registry Number |
208921-02-2 |
| SMILES |
Not Available |
| Chemical Structure |
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| ADRs Induced by Drug |
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