Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Trimipramine maleate
Drug ID BADD_D02295
Description Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Indications and Usage For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
Marketing Status approved
ATC Code N06AA06
DrugBank ID DB00726
KEGG ID D02408
MeSH ID D014299
PubChem ID 5282318
TTD Drug ID D00HZV
NDC Product Code 42806-803; 67763-118; 42806-802; 51991-945; 51991-944; 64850-850; 72162-2063; 64850-851; 72162-2061; 72162-2062; 45562-1739; 51991-946; 64850-852; 50396-7518; 42806-804
UNII 269K6498LD
Synonyms Trimipramine | Trimeprimine | 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine | Trimipramine, (-)-Isomer | Herphonal | Trimineurin | Novo-Tripramine | Novo Tripramine | NovoTripramine | Nu-Trimipramine | Nu Trimipramine | NuTrimipramine | Rhotrimine | Stangyl | Surmontil | Surmontil Maleate | Trimidura | Trimineurin Maleate | Trimipramin AZU | Trimipramin Beta | Beta, Trimipramin | Trimipramin Stada | Trimipramin-Neurazpharm | Trimipramin Neurazpharm | TrimipraminNeurazpharm | Trimipramine Maleate | Trimipramine Maleate (1:1) | Trimipramine Maleate (1:1), (+)-Isomer | Trimipramine Maleate (1:1), (+-)-Isomer | Trimipramine Maleate (1:1), (-)-Isomer | Trimipramine Mesylate | Trimipramine Monohydrochloride | Trimipramine, (+-)-Isomer | Eldoral | Apo-Trimip | Apo Trimip | ApoTrimip
Chemical Information
Molecular Formula C24H30N2O4
CAS Registry Number 521-78-8
SMILES CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.C(=CC(=O)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypomania19.16.02.001--Not Available
Hypotension24.06.03.002--
Ileus paralytic07.02.05.001--Not Available
Insomnia17.15.03.002; 19.02.01.002--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Liver function test abnormal13.03.04.030--Not Available
Malaise08.01.01.003--
Micturition disorder20.02.02.005--Not Available
Mydriasis17.02.11.003; 06.05.03.004--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Neuropathy peripheral17.09.03.003--Not Available
Nightmare19.02.03.003--Not Available
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Parotid gland enlargement07.06.03.001--Not Available
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Photosensitivity reaction23.03.09.003--
Pollakiuria20.02.02.007--
Pruritus23.03.12.001--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Rash23.03.13.001--Not Available
Restlessness19.11.02.002; 17.02.05.021--
Seizure17.12.03.001--
Somnolence19.02.05.003; 17.02.04.006--
Stomatitis07.05.06.005--
Tachycardia02.03.02.007--Not Available
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