Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Trimipramine maleate
Drug ID BADD_D02295
Description Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.
Indications and Usage For the treatment of depression and depression accompanied by anxiety, agitation or sleep disturbance
Marketing Status approved
ATC Code N06AA06
DrugBank ID DB00726
KEGG ID D02408
MeSH ID D014299
PubChem ID 5282318
TTD Drug ID D00HZV
NDC Product Code 42806-803; 67763-118; 42806-802; 51991-945; 51991-944; 64850-850; 72162-2063; 64850-851; 72162-2061; 72162-2062; 45562-1739; 51991-946; 64850-852; 50396-7518; 42806-804
UNII 269K6498LD
Synonyms Trimipramine | Trimeprimine | 10,11 Dihydro-N,N,beta-trimethyl-5H-dibenz(b,f)azepine-5-propanamine | Trimipramine, (-)-Isomer | Herphonal | Trimineurin | Novo-Tripramine | Novo Tripramine | NovoTripramine | Nu-Trimipramine | Nu Trimipramine | NuTrimipramine | Rhotrimine | Stangyl | Surmontil | Surmontil Maleate | Trimidura | Trimineurin Maleate | Trimipramin AZU | Trimipramin Beta | Beta, Trimipramin | Trimipramin Stada | Trimipramin-Neurazpharm | Trimipramin Neurazpharm | TrimipraminNeurazpharm | Trimipramine Maleate | Trimipramine Maleate (1:1) | Trimipramine Maleate (1:1), (+)-Isomer | Trimipramine Maleate (1:1), (+-)-Isomer | Trimipramine Maleate (1:1), (-)-Isomer | Trimipramine Mesylate | Trimipramine Monohydrochloride | Trimipramine, (+-)-Isomer | Eldoral | Apo-Trimip | Apo Trimip | ApoTrimip
Chemical Information
Molecular Formula C24H30N2O4
CAS Registry Number 521-78-8
SMILES CC(CN1C2=CC=CC=C2CCC3=CC=CC=C31)CN(C)C.C(=CC(=O)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Testicular swelling21.13.01.003--Not Available
Thrombocytopenia01.08.01.002--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tongue discolouration07.14.02.006--Not Available
Tongue oedema23.04.01.009; 10.01.05.008; 07.14.02.007--Not Available
Tremor17.01.06.002--
Ureteric dilatation20.06.01.007--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Epigastric discomfort07.01.02.004--Not Available
Inappropriate antidiuretic hormone secretion14.05.07.001; 05.03.03.001--Not Available
Weight abnormal13.15.01.016--Not Available
Libido disorder19.08.03.004; 21.03.02.006--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Erectile dysfunction21.03.01.007; 19.08.04.001--
Urinary tract obstruction20.08.01.004--
Psychotic disorder19.03.01.002--
Bone marrow failure01.03.03.005--
Product taste abnormal27.02.02.001--Not Available
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