| Drug Name |
Tropisetron |
| Drug ID |
BADD_D02304 |
| Description |
Tropisetron is an indole derivative with antiemetic activity. As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.
Tropisetron appears to be well tolerated with the most frequently reported adverse effect being headache. Extrapyramidal side effects are rare upon using tropisetron. |
| Indications and Usage |
For the prevention of nausea and vomiting induced by cytotoxic therapy and postoperative. |
| Marketing Status |
approved; investigational |
| ATC Code |
A04AA03 |
| DrugBank ID |
DB11699
|
| KEGG ID |
D02130
|
| MeSH ID |
D000077526
|
| PubChem ID |
656665
|
| TTD Drug ID |
D0K0KH
|
| NDC Product Code |
Not Available |
| UNII |
6I819NIK1W
|
| Synonyms |
Tropisetron | Navoban | (3 alpha-Tropanyl)-1H-indole-3-carboxylic Acid Ester | Indole-3-carboxylic Acid Tropine Ester | Indole 3 carboxylic Acid Tropine Ester | ICS 205-930 | ICS 205 930 | ICS 205930 | ICS-205-930 | ICS-205930 | Tropisetron Hydrochloride |
