Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Valdecoxib
Drug ID BADD_D02325
Description Valdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Indications and Usage For the treatment of osteoarthritis and dysmenorrhoea
Marketing Status approved; investigational; withdrawn
ATC Code M01AH03
DrugBank ID DB00580
KEGG ID D02709
MeSH ID C406224
PubChem ID 119607
TTD Drug ID D0L6DA
NDC Product Code Not Available
UNII 2919279Q3W
Synonyms valdecoxib | Bextra | SC 65872 | SC-65872
Chemical Information
Molecular Formula C16H14N2O3S
CAS Registry Number 181695-72-7
SMILES CC1=C(C(=NO1)C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injury12.01.08.004--Not Available
Insomnia19.02.01.002; 17.15.03.002--
Intermittent claudication24.04.03.001--Not Available
Intestinal obstruction07.13.01.002--Not Available
Keratitis06.04.02.002--
Laryngitis22.07.03.001; 11.01.13.001--
Leukocytosis01.02.01.002--
Leukopenia01.02.02.001--Not Available
Lipoma16.18.01.001; 15.09.01.001--Not Available
Loss of consciousness17.02.04.004--Not Available
Lymphadenopathy01.09.01.002--Not Available
Lymphangitis01.09.01.005; 24.09.02.001; 11.01.15.001--Not Available
Lymphopenia01.02.02.002--Not Available
Malaise08.01.01.003--
Malignant melanoma23.08.01.001; 16.03.01.001--Not Available
Malignant ovarian cyst21.11.01.001; 16.12.04.002--Not Available
Mania19.16.02.002--
Mastitis21.05.03.002; 11.01.02.001--
Melaena24.07.02.013; 07.12.02.004--Not Available
Menopausal symptoms21.02.02.002--Not Available
Menstrual disorder21.01.01.004--Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mitral valve incompetence02.07.01.002--Not Available
Multiple fractures15.08.02.005; 12.04.02.009--Not Available
Muscle twitching15.05.03.005--Not Available
Myalgia15.05.02.001--
Myocardial infarction02.02.02.007; 24.04.04.009--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Nausea07.01.07.001--
Neoplasm16.16.02.001--Not Available
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