Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vecuronium bromide
Drug ID BADD_D02341
Description Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.
Indications and Usage Vecuronium is a muscle relaxing agent and is used as an adjunct in general anesthesia.
Marketing Status approved; investigational
ATC Code M03AC03
DrugBank ID DB01339
KEGG ID D00767
MeSH ID D014673
PubChem ID 39764
TTD Drug ID D0Z8HG
NDC Product Code 68083-139; 0409-1632; 10695-021; 47335-932; 63323-782; 55150-235; 0143-9234; 51662-1475; 55486-1566; 67457-475; 55150-236; 67457-438; 53183-1308; 60870-0297; 63323-781; 60722-1008; 47335-931; 68083-140; 0703-2914; 51662-1547; 81565-206; 0143-9232
UNII 7E4PHP5N1D
Synonyms Vecuronium Bromide | Bromide, Vecuronium | Vecuronium Hydrobromide | Hydrobromide, Vecuronium | Norcuron | Vecuronium | Vecuronium Phosphate | Phosphate, Vecuronium | Vecuronium Citrate | Citrate, Vecuronium | Vecuronium Hydrochloride | Hydrochloride, Vecuronium | Vecuronium Maleate | Maleate, Vecuronium | NC-45 | NC 45 | NC45 | ORG-NC45 | ORG NC45 | ORG-NC 45 | ORG NC 45 | ORGNC 45 | ORG-NC-45 | ORGNC45 | Vecuronium Bromide, Quaternary Ion
Chemical Information
Molecular Formula C34H57BrN2O4
CAS Registry Number 50700-72-6
SMILES CC(=O)OC1CC2CCC3C(C2(CC1N4CCCCC4)C)CCC5(C3CC(C5OC(=O)C)[N+]6(CCCCC6)C)C.[Br-]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Respiratory failure22.02.06.002; 14.01.04.003--
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Tachycardia02.03.02.0070.000057%Not Available
Therapeutic response increased08.06.01.021--Not Available
Unresponsive to stimuli17.02.05.0310.000125%Not Available
Urticaria10.01.06.001; 23.04.02.001--
Airway complication of anaesthesia12.02.20.001; 22.02.07.006--Not Available
Angiopathy24.03.02.007--Not Available
Cardiac disorder02.11.01.003--Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
Mediastinal disorder22.09.03.001--Not Available
Pulmonary function test decreased13.19.01.001--Not Available
Brain injury19.07.03.007; 17.11.01.0030.000057%Not Available
Therapeutic product effect decreased08.06.01.0500.000154%Not Available
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