Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vidarabine monohydrate
Drug ID BADD_D02354
Description A nucleoside antibiotic isolated from Streptomyces antibioticus. It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the herpes viruses, the vaccinia VIRUS and varicella zoster virus.
Indications and Usage For treatment of chickenpox - varicella, herpes zoster and herpes simplex
Marketing Status approved; investigational
ATC Code S01AD06; J05AB03
DrugBank ID DB00194
KEGG ID D00406
MeSH ID D014740
PubChem ID 32326
TTD Drug ID D0NI0C
NDC Product Code Not Available
UNII FA2DM6879K
Synonyms Vidarabine | beta-Ara A | beta Ara A | Adenine Arabinoside | Arabinoside, Adenine | alpha-D-Arabinofuranosyladenine | alpha D Arabinofuranosyladenine | Ara A | alpha-Ara A | alpha Ara A | Arabinofuranosyladenine | Arabinosyladenine | 9-beta-D-Arabinofuranosyladenine | 9 beta D Arabinofuranosyladenine | 9-beta-Arabinofuranosyladenine | 9 beta Arabinofuranosyladenine | Ara-A | Vira-A | Vira A | ViraA
Chemical Information
Molecular Formula C10H15N5O5
CAS Registry Number 24356-66-9
SMILES C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N.O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Corneal oedema06.04.02.001--Not Available
Glaucoma06.03.01.002--
Hypersensitivity10.01.03.003--
Hyphaema24.07.05.004; 12.01.04.007; 06.07.04.001--Not Available
Lacrimation increased06.08.02.004--
Pain08.01.08.004--
Photophobia17.17.02.006; 06.01.01.004--
Punctate keratitis06.04.02.003--Not Available
Skin irritation23.03.04.009--Not Available
Uveitis10.02.01.023; 06.04.03.003--
Conjunctival hyperaemia06.04.01.004--Not Available
Vascular occlusion24.04.02.015--Not Available
Corneal neovascularisation24.03.07.009; 06.07.01.003--Not Available
Sensation of foreign body08.01.09.002--Not Available
Nutritional condition abnormal13.15.01.014--Not Available
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