Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Vilazodone hydrochloride
Drug ID BADD_D02356
Description Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Indications and Usage Vilazodone is approved for treatment of major depressive disorder.[Label,A38477,A177622]
Marketing Status approved
ATC Code N06AX24
DrugBank ID DB06684
KEGG ID D09699
MeSH ID D000069503
PubChem ID 6918313
TTD Drug ID D0X6BV
NDC Product Code 0456-1141; 65129-2248; 16729-353; 55111-955; 65015-848; 16729-354; 55154-4624; 60505-4773; 0480-2044; 72603-127; 76282-545; 50370-0035; 65372-1203; 60505-4772; 0480-2043; 0480-2045; 60505-4774; 69097-981; 76282-544; 66039-903; 16729-352; 46708-233; 62332-232; 0456-1110; 46708-232; 69097-982; 72603-125; 46708-234; 0456-1100; 0456-1101; 76282-546; 51407-691; 55154-4627; 0456-1140; 72603-126; 0456-1111; 51407-692; 51407-693; 62332-233; 62332-234; 0456-1120; 69097-979; 0456-1121
UNII U8HTX2GK8J
Synonyms Vilazodone Hydrochloride | Hydrochloride, Vilazodone | 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1) | Vilazodone HCl | HCl, Vilazodone | Viibryd | EMD 68843 | 68843, EMD | EMB-68843 | EMB 68843 | EMB68843 | Vilazodone | 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide
Chemical Information
Molecular Formula C26H28ClN5O2
CAS Registry Number 163521-08-2
SMILES C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Mania19.16.02.002--
Migraine24.03.05.003; 17.14.02.001--Not Available
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.003--Not Available
Night sweats23.02.03.006; 08.01.03.031--Not Available
Orgasm abnormal21.03.02.013; 19.08.01.004--
Palpitations02.11.04.012--
Panic attack19.06.04.001--Not Available
Paraesthesia17.02.06.005; 23.03.03.094--
Pollakiuria20.02.02.007--
Restlessness19.11.02.002; 17.02.05.021--
Sedation17.02.04.005--Not Available
Seizure17.12.03.001--
Serotonin syndrome15.05.04.016; 12.03.01.041; 17.05.02.004--Not Available
Sexual dysfunction21.03.02.003; 19.08.05.002--Not Available
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Suicidal ideation19.12.01.003--
Suicide attempt19.12.01.004--
Tremor17.01.06.002--
Ventricular extrasystoles02.03.04.007--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Vomiting07.01.07.003--
Musculoskeletal discomfort15.03.04.001--Not Available
Disturbance in sexual arousal19.08.04.003--Not Available
Breast disorder21.05.04.004--Not Available
Cardiac disorder02.11.01.003--Not Available
Connective tissue disorder10.04.04.026; 15.06.01.006--Not Available
Malnutrition14.03.02.004--Not Available
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