Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vilazodone hydrochloride
Drug ID BADD_D02356
Description Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Indications and Usage Vilazodone is approved for treatment of major depressive disorder.[Label,A38477,A177622]
Marketing Status approved
ATC Code N06AX24
DrugBank ID DB06684
KEGG ID D09699
MeSH ID D000069503
PubChem ID 6918313
TTD Drug ID D0X6BV
NDC Product Code 0456-1141; 65129-2248; 16729-353; 55111-955; 65015-848; 16729-354; 55154-4624; 60505-4773; 0480-2044; 72603-127; 76282-545; 50370-0035; 65372-1203; 60505-4772; 0480-2043; 0480-2045; 60505-4774; 69097-981; 76282-544; 66039-903; 16729-352; 46708-233; 62332-232; 0456-1110; 46708-232; 69097-982; 72603-125; 46708-234; 0456-1100; 0456-1101; 76282-546; 51407-691; 55154-4627; 0456-1140; 72603-126; 0456-1111; 51407-692; 51407-693; 62332-233; 62332-234; 0456-1120; 69097-979; 0456-1121
UNII U8HTX2GK8J
Synonyms Vilazodone Hydrochloride | Hydrochloride, Vilazodone | 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1) | Vilazodone HCl | HCl, Vilazodone | Viibryd | EMD 68843 | 68843, EMD | EMB-68843 | EMB 68843 | EMB68843 | Vilazodone | 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide
Chemical Information
Molecular Formula C26H28ClN5O2
CAS Registry Number 163521-08-2
SMILES C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Mental disorder19.07.01.002--Not Available
Decreased appetite08.01.09.028; 14.03.01.005--
Erectile dysfunction21.03.01.007; 19.08.04.001--
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