| Pharmaceutical Information |
| Drug Name |
Vinblastine sulfate |
| Drug ID |
BADD_D02359 |
| Description |
Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.) |
| Indications and Usage |
For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma. |
| Marketing Status |
approved |
| ATC Code |
L01CA01 |
| DrugBank ID |
DB00570
|
| KEGG ID |
D01068
|
| MeSH ID |
D014747
|
| PubChem ID |
5388983
|
| TTD Drug ID |
D0W9MM
|
| NDC Product Code |
53104-7504; 63323-278; 48954-588 |
| UNII |
N00W22YO2B
|
| Synonyms |
Vinblastine | Vincaleukoblastine | Lemblastine | Velban | Vinblastina Lilly | Velbe | Vinblastine Sulfate | Sulfate, Vinblastine | Vinblastinsulfat-Gry | Cellblastin | Vinblastin Hexal |
|
| Chemical Information |
| Molecular Formula |
C46H58N4O9.H2O4S |
| CAS Registry Number |
143-67-9 |
| SMILES |
CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8
N6C)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O.OS(=O)(=O)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Bone marrow failure | 01.03.03.005 | - | - | |
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