Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Zanamivir
Drug ID BADD_D02380
Description A guanido-neuraminic acid that is used to inhibit neuraminidase.
Indications and Usage For the prevention and treatment of influenza A and B.
Marketing Status approved; investigational
ATC Code J05AH01
DrugBank ID DB00558
KEGG ID D00902
MeSH ID D053243
PubChem ID 60855
TTD Drug ID D00NPP
NDC Product Code 0173-0681; 63379-028
UNII L6O3XI777I
Synonyms Zanamivir | 2,3-Didehydro-2,4-Dideoxy-4-Guanidinyl-N-Acetylneuraminic Acid | 4-Guanidino-2,4-Dideoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 5-Acetylamino-2,6-Anhydro-4-Guanidino-3,4,5-Trideoxy-D-Galacto-Non-Enoic Acid | 4-Guanidino-Neu5Ac2en | 4 Guanidino Neu5Ac2en | 2,3-Didehydro-2,4-Dideoxy-4-Guanidino-N-Acetyl-D-Neuraminic Acid | 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic Acid | 4 Guanidino 2 Deoxy 2,3 Didehydro N Acetylneuraminic Acid | Acid, 4-Guanidino-2-Deoxy-2,3-Didehydro-N-Acetylneuraminic | Relenza | GG 167 | GG167 | GG-167
Chemical Information
Molecular Formula C12H20N4O7
CAS Registry Number 139110-80-8
SMILES CC(=O)NC1C(C=C(OC1C(C(CO)O)O)C(=O)O)N=C(N)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.0020.000282%
Acute respiratory distress syndrome24.03.02.034; 10.02.01.067; 22.01.03.0010.000847%
Acute respiratory failure22.02.06.001; 14.01.04.0040.000282%Not Available
Ageusia07.14.03.003; 17.02.07.0010.000282%Not Available
Aggression19.05.01.0010.000706%Not Available
Agitation19.06.02.001; 17.02.05.0120.001044%
Altered state of consciousness19.07.01.003; 17.02.04.0010.000988%Not Available
Anaphylactic reaction24.06.03.006; 10.01.07.0010.000423%
Anaphylactic shock24.06.02.004; 10.01.07.0020.000282%Not Available
Anaphylactoid reaction24.06.03.007; 10.01.07.003--Not Available
Anxiety19.06.02.002--
Arrhythmia02.03.02.001--Not Available
Arthralgia15.01.02.001--
Asthenia08.01.01.001--Not Available
Asthma22.03.01.002; 10.01.03.0100.000282%Not Available
Blister23.03.01.001; 12.01.06.0020.000423%Not Available
Body temperature increased13.15.01.001--Not Available
Bronchitis22.07.01.001; 11.01.09.001--
Bronchospasm22.03.01.004; 10.01.03.012--
Cardiac arrest02.03.04.0010.000565%
Chills15.05.03.016; 08.01.09.001--
Confusional state19.13.01.001; 17.02.03.005--
Cough22.02.03.0010.000423%
Death08.04.01.0010.003528%
Dehydration14.05.05.0010.000282%
Delirium19.13.02.0010.001327%
Delusion19.10.01.001--
Depressed level of consciousness17.02.04.0020.000988%
Dermatitis23.03.04.002--Not Available
Diarrhoea07.02.01.0010.001552%
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