Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vilazodone
Drug ID BADD_D02456
Description Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Indications and Usage Vilazodone is approved for treatment of major depressive disorder.[Label,A38477,A177622]
Marketing Status approved
ATC Code N06AX24
DrugBank ID DB06684
KEGG ID D09698
MeSH ID D000069503
PubChem ID 6918314
TTD Drug ID D0X6BV
NDC Product Code Not Available
UNII S239O2OOV3
Synonyms Vilazodone Hydrochloride | Hydrochloride, Vilazodone | 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1) | Vilazodone HCl | HCl, Vilazodone | Viibryd | EMD 68843 | 68843, EMD | EMB-68843 | EMB 68843 | EMB68843 | Vilazodone | 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide
Chemical Information
Molecular Formula C26H27N5O2
CAS Registry Number 163521-12-8
SMILES C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.004281%Not Available
Abdominal distension07.01.04.0010.001246%
Abnormal dreams17.15.02.001; 19.02.03.0010.013576%Not Available
Acne23.02.01.0010.001246%Not Available
Ageusia17.02.07.001; 07.14.03.0030.001246%Not Available
Aggression19.05.01.0010.004281%Not Available
Agitation19.06.02.001; 17.02.05.0120.008337%
Akathisia17.01.02.002; 19.06.02.0060.000703%
Alopecia23.02.02.0010.005367%
Altered state of consciousness19.07.01.003; 17.02.04.0010.000319%Not Available
Amnesia19.20.01.001; 17.03.02.0010.001342%
Anger19.04.02.0010.002651%Not Available
Anosmia22.04.03.006; 17.04.04.0010.000703%
Anxiety19.06.02.0020.013512%
Aura17.02.07.0110.000703%Not Available
Bladder discomfort20.02.02.0190.001086%Not Available
Breast tenderness21.05.05.0040.000703%Not Available
Bruxism07.01.06.008; 19.11.03.0010.000319%Not Available
Chest discomfort22.12.02.002; 02.02.02.009; 08.01.08.0190.002172%Not Available
Completed suicide19.12.01.001; 08.04.01.0100.003674%Not Available
Confusional state19.13.01.001; 17.02.03.0050.003674%
Coordination abnormal17.02.02.0040.000862%Not Available
Crying08.01.03.005; 19.04.02.002; 17.02.05.013; 12.02.11.0010.003833%Not Available
Delirium19.13.02.0010.000319%
Depressed mood19.15.02.0010.000703%Not Available
Depression19.15.01.0010.007826%
Diabetic ketoacidosis14.07.03.001; 05.07.03.0010.000319%Not Available
Diarrhoea07.02.01.0010.028494%
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.0020.000319%Not Available
Disorientation19.13.01.002; 17.02.05.0150.000639%Not Available
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