Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Vilazodone
Drug ID BADD_D02456
Description Vilazodone is a novel compound with combined high affinity and selectivity for the 5-hydroxytryptamine (5-HT) transporter and 5-HT(1A) receptors[Label,A177622]. Vilazodone may also be associated with less sexual dysfunction and weight gain[A6947]. Vilazodone was given FDA approval on January 21, 2011[L6046,A177622].
Indications and Usage Vilazodone is approved for treatment of major depressive disorder.[Label,A38477,A177622]
Marketing Status approved
ATC Code N06AX24
DrugBank ID DB06684
KEGG ID D09698
MeSH ID D000069503
PubChem ID 6918314
TTD Drug ID D0X6BV
NDC Product Code Not Available
UNII S239O2OOV3
Synonyms Vilazodone Hydrochloride | Hydrochloride, Vilazodone | 2-benzofurancarboxamide, 5-(4-(4-(5-cyano-1H-indol-3-yl)butyl)-1-piperazinyl)-, hydrochloride (1:1) | Vilazodone HCl | HCl, Vilazodone | Viibryd | EMD 68843 | 68843, EMD | EMB-68843 | EMB 68843 | EMB68843 | Vilazodone | 5-(4-(4-(5-cyano-3-indolyl)butyl)-1-piperazinyl)benzofuran-2-carboxamide
Chemical Information
Molecular Formula C26H27N5O2
CAS Registry Number 163521-12-8
SMILES C1CN(CCN1CCCCC2=CNC3=C2C=C(C=C3)C#N)C4=CC5=C(C=C4)OC(=C5)C(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle tightness15.05.03.0070.000703%Not Available
Dysstasia15.03.05.011; 08.01.03.089; 17.02.02.0120.000319%Not Available
Musculoskeletal stiffness15.03.05.0270.001022%Not Available
Inappropriate antidiuretic hormone secretion14.05.07.001; 05.03.03.0010.000319%Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.0030.000703%Not Available
Restless legs syndrome17.02.07.008; 15.05.03.0120.001086%Not Available
Abnormal behaviour19.01.01.0010.001725%Not Available
Erectile dysfunction21.03.01.007; 19.08.04.0010.000862%
Psychotic disorder19.03.01.0020.001597%
Unevaluable event08.01.03.0510.001565%Not Available
Slow speech19.19.02.004; 17.02.08.0160.001086%Not Available
Anal incontinence17.05.01.021; 07.01.06.0290.001086%
Impulsive behaviour19.18.01.0010.001086%Not Available
Violence-related symptom19.05.01.0220.000703%Not Available
Tachyphrenia19.10.03.010; 17.03.03.0070.000319%Not Available
Electric shock sensation17.02.07.024; 08.06.02.0230.001949%Not Available
Taste disorder17.02.07.029; 07.14.03.0040.001629%Not Available
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