Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Aclidinium
Drug ID BADD_D02465
Description Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD). It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.
Indications and Usage Aclidinium bromide inhalation powder is indicated for the long-term, maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Marketing Status approved
ATC Code Not Available
DrugBank ID DB08897
KEGG ID Not Available
MeSH ID Not Available
PubChem ID 11434515
TTD Drug ID D0VP1V
NDC Product Code Not Available
UNII K17VY42F6C
Synonyms Not Available
Chemical Information
Molecular Formula C26H30NO4S2+
CAS Registry Number 727649-81-2
SMILES C1C[N+]2(CCC1C(C2)OC(=O)C(C3=CC=CS3)(C4=CC=CS4)O)CCCOC5=CC=CC=C5
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Lip swelling23.04.01.007; 10.01.05.005; 07.05.04.0050.000955%Not Available
Loss of consciousness17.02.04.0040.001172%Not Available
Lung disorder22.02.07.0010.001476%Not Available
Malaise08.01.01.0030.003516%
Memory impairment19.20.01.003; 17.03.02.0030.001693%
Nasal congestion22.04.04.0010.001693%
Nasal dryness22.04.03.002--Not Available
Oedema mouth23.04.01.008; 07.05.04.001; 10.01.05.0060.000434%Not Available
Oral pain07.05.05.0340.001476%
Pneumothorax22.05.02.0030.000434%
Productive cough22.02.03.0050.000434%
Pruritus23.03.12.0010.001389%
Rash23.03.13.0010.003733%Not Available
Rash pruritic23.03.13.0300.002214%Not Available
Respiration abnormal22.02.01.0410.001476%Not Available
Respiratory disorder22.02.07.0020.001476%Not Available
Stomatitis07.05.06.0050.000955%
Swelling08.01.03.0150.000955%Not Available
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.0030.000651%Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.000434%
Tachycardia02.03.02.0070.001172%Not Available
Throat irritation22.12.03.029; 07.05.05.0370.001910%Not Available
Throat tightness22.12.03.031; 19.01.02.0050.000434%Not Available
Tremor17.01.06.0020.001476%
Urinary retention20.02.02.0110.001085%
Urticaria23.04.02.001; 10.01.06.0010.001693%
Vision blurred17.17.01.010; 06.02.06.0070.001085%
Wheezing22.03.01.0090.003906%
Hypoacusis04.02.01.0060.002951%
Peripheral swelling08.01.03.053; 02.05.04.015--Not Available
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