Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Calcium
Drug ID BADD_D02539
Description Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled conditions. Circulating calcium is either in the free, ionized form or bound to blood proteins such as serum albumin. Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium. Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. Calcium gluconate and calcium lactate are absorbed well by pregnant women. Seniors absorb calcium lactate, gluconate and citrate better unless they take their calcium supplement with a full breakfast.
Indications and Usage Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
Marketing Status nutraceutical
ATC Code Not Available
DrugBank ID DB01373
KEGG ID Not Available
MeSH ID D002118
PubChem ID 5460341
TTD Drug ID D0PJ4K
NDC Product Code 55259-0002; 55259-0001; 55259-0007
UNII SY7Q814VUP
Synonyms Calcium | Blood Coagulation Factor IV | Coagulation Factor IV | Factor IV, Coagulation | Calcium-40 | Calcium 40 | Factor IV
Chemical Information
Molecular Formula Ca
CAS Registry Number 7440-70-2
SMILES [Ca]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Visual impairment06.02.10.0130.001840%Not Available
Vomiting07.01.07.0030.001957%
Tubulointerstitial nephritis20.05.02.0020.000391%Not Available
Hypoacusis04.02.01.0060.000783%
Peripheral swelling08.01.03.053; 02.05.04.0150.000979%Not Available
Osteopenia14.04.04.004; 15.02.03.0030.000587%Not Available
General physical health deterioration08.01.03.0180.001370%Not Available
Balance disorder08.01.03.081; 17.02.02.0070.000587%Not Available
Musculoskeletal chest pain22.09.01.001; 15.03.04.0120.000391%
Deep vein thrombosis24.01.02.0030.000979%Not Available
Injection site discolouration23.03.03.046; 12.07.03.038; 08.02.03.0380.000861%Not Available
Eyelids pruritus23.03.12.005; 06.08.03.0070.001996%Not Available
Calciphylaxis14.04.01.0120.002740%Not Available
Eye pruritus06.04.05.0060.001331%Not Available
Injection site swelling12.07.03.018; 08.02.03.0170.000861%Not Available
Bone metabolism disorder15.02.03.009; 14.04.04.0090.000391%Not Available
Prostate cancer21.04.02.002; 16.25.01.0010.000587%Not Available
Cardiac disorder02.11.01.0030.000783%Not Available
Inflammation10.02.01.089; 08.01.05.0070.000391%Not Available
Limb discomfort15.03.04.0140.000391%Not Available
Lipid metabolism disorder14.08.04.0030.000391%Not Available
Ischaemia24.04.02.0040.000861%Not Available
Adverse drug reaction08.06.01.0090.000391%Not Available
Renal impairment20.01.03.0100.000587%Not Available
Osteonecrosis of jaw24.04.05.005; 15.02.04.0100.001174%
Chronic kidney disease20.01.03.0170.000391%
Pulmonary arterial hypertension24.08.03.003; 22.06.01.0020.000391%Not Available
Bone loss15.02.04.0200.000391%Not Available
Treatment failure08.06.01.0170.001057%Not Available
Low birth weight baby18.04.02.0030.000783%Not Available
The 6th Page    First    Pre   6 7    Next   Last    Total 7 Pages