Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Daridorexant
Drug ID BADD_D02547
Description Nemorexant is under investigation in clinical trial NCT03101189 (A Study of ACT-541468 in Healthy Japanese and Caucasian Subjects).
Indications and Usage Not Available
Marketing Status investigational
ATC Code Not Available
DrugBank ID DB15031
KEGG ID D11886
MeSH ID C000634383
PubChem ID 91801202
TTD Drug ID Not Available
NDC Product Code 80491-7825; 80491-7850
UNII LMQ24G57E9
Synonyms daridorexant | nemorexant | methanone, ((2S)-2-(6-chloro-7-methyl-1H-benzimidazol-2-yl)-2-methyl-1-pyrrolidinyl)(5-methoxy-2-(2H-1,2,3-traizol-2-yl)phenyl)- | ((S)-(2-(5-chloro-4-methyl-1H-benzo(d)imidazol-2-yl)-2-methylpyrrolidin-1-yl) (5 methoxy-2-(2H-1,2,3-triazol-2-yl)phenyl)methanone) | ACT-541468
Chemical Information
Molecular Formula C23H23ClN6O2
CAS Registry Number 1505484-82-1
SMILES CC1=C(C=CC2=C1N=C(N2)C3(CCCN3C(=O)C4=C(C=CC(=C4)OC)N5N=CC=N5)C)Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams17.15.02.001; 19.02.03.001-Not Available
Agitation19.06.02.001; 17.02.05.012-
Confusional state19.13.01.001; 17.02.03.005-
Depression19.15.01.001-
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.006-
Drug ineffective08.06.01.006-Not Available
Dry mouth07.06.01.002-
Feeling abnormal08.01.09.014-Not Available
Hallucination19.10.04.003-
Hangover08.01.09.018-Not Available
Hypersensitivity10.01.03.003-
Insomnia17.15.03.002; 19.02.01.002-
Night sweats23.02.03.006; 08.01.03.031-Not Available
Nightmare19.02.03.003-Not Available
Sleep paralysis19.02.02.004; 17.15.02.005-Not Available
Sleep terror19.02.03.008; 17.15.02.006-Not Available
Somnambulism19.02.03.006; 17.15.02.004-Not Available
Somnolence17.02.04.006; 19.02.05.003-
Suicidal ideation19.12.01.003-
Restless legs syndrome17.02.07.008; 15.05.03.012-Not Available
Unevaluable event08.01.03.051-Not Available
Therapeutic product effect incomplete08.06.01.052-Not Available
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