Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Deucravacitinib
Drug ID BADD_D02549
Description Deucravacitinib is under investigation in clinical trial NCT04772079 (A Study to Evaluate the Drug Levels, Efficacy and Safety of BMS-986165 in Adolescent Participants With Moderate to Severe Plaque Psoriasis).
Indications and Usage Not Available
Marketing Status investigational
ATC Code L04AA56
DrugBank ID DB16650
KEGG ID D11817
MeSH ID C000628674
PubChem ID 134821691
TTD Drug ID Not Available
NDC Product Code 0003-0895; 50193-4323; 63285-893
UNII N0A21N6RAU
Synonyms deucravacitinib | BMS-986165
Chemical Information
Molecular Formula C20H22N8O3
CAS Registry Number 1609392-27-9
SMILES CNC(=O)C1=NN=C(C=C1NC2=CC=CC(=C2OC)C3=NN(C=N3)C)NC(=O)C4CC4
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.0010.001230%Not Available
Abdominal pain upper07.01.05.0030.000530%
Acne23.02.01.0010.014756%Not Available
Acne cystic23.02.01.0050.000820%Not Available
Back pain15.03.04.0050.000820%
Blister23.03.01.001; 12.01.06.0020.000820%Not Available
Burning sensation17.02.06.001; 08.01.09.0290.001640%Not Available
Chills15.05.03.016; 08.01.09.0010.001230%
Chromaturia20.02.01.0020.000820%
Condition aggravated08.01.03.0040.001350%Not Available
Constipation07.02.02.0010.001230%
Cough22.02.03.0010.001640%
Dehydration14.05.05.0010.000241%
Dermatitis allergic10.01.03.014; 23.03.04.0030.000820%Not Available
Diarrhoea07.02.01.0010.002700%
Erythema23.03.06.0010.006679%Not Available
Gastrointestinal disorder07.11.01.0010.000820%Not Available
Headache17.14.01.0010.003689%
Hypersensitivity10.01.03.0030.001640%
Insomnia19.02.01.002; 17.15.03.0020.001640%
Lethargy19.04.04.004; 17.02.04.003; 08.01.01.0080.000530%
Lip swelling23.04.01.007; 07.05.04.005; 10.01.05.0050.000820%Not Available
Malaise08.01.01.0030.002049%
Mouth ulceration07.05.06.0040.007788%Not Available
Myalgia15.05.02.0010.001640%
Nephrolithiasis20.04.01.0020.000241%
Oral mucosal blistering07.05.05.0170.000820%Not Available
Oral pain07.05.05.0340.001640%
Photosensitivity reaction23.03.09.0030.000820%
Pruritus23.03.12.0010.007499%
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