Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Tapinarof
Drug ID BADD_D02597
Description Tapinarof is targeted as a topical cream treatment for psoriasis, a chronic autoimmune skin disease.
Indications and Usage Investigated for use/treatment in psoriasis and psoriatic disorders.
Marketing Status investigational
ATC Code Not Available
DrugBank ID DB06083
KEGG ID D11365
MeSH ID C571829
PubChem ID 6439522
TTD Drug ID D03DMB
NDC Product Code 58175-0646; 81672-5051; 61187-101
UNII 84HW7D0V04
Synonyms tapinarof | 3,5-dihydroxy-4-isopropylstilbene | benvitimod | 3,5-DH4IS | GSK2894512 | 2-isopropyl-5-(2-phenylethenyl)benzene-1,3-diol | 5-(2-phenylethenyl)-2-isopropyl-1,3-benzenediol | WBI-1001
Chemical Information
Molecular Formula C17H18O2
CAS Registry Number 79338-84-4
SMILES CC(C)C1=C(C=C(C=C1O)C=CC2=CC=CC=C2)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001-Not Available
Acne23.02.01.001-Not Available
Application site erythema23.03.06.005; 12.07.01.001; 08.02.01.001-Not Available
Application site irritation12.07.01.003; 08.02.01.003-Not Available
Application site pain12.07.01.004; 08.02.01.004-Not Available
Application site pruritus23.03.12.004; 12.07.01.005; 08.02.01.005-Not Available
Application site rash23.03.13.008; 12.07.01.016; 08.02.01.016-Not Available
Dermatitis contact23.03.04.004; 12.03.01.040; 10.01.01.003-Not Available
Erythema23.03.06.001-Not Available
Eyelid oedema06.04.04.004; 23.04.01.003; 10.01.05.001-Not Available
Headache17.14.01.001-
Hypersensitivity10.01.03.003-
Influenza like illness08.01.03.010-
Milia23.02.03.011-Not Available
Pain of skin23.03.03.003-
Pruritus23.03.12.001-
Psoriasis23.03.14.002; 10.02.01.036-Not Available
Rash23.03.13.001-Not Available
Skin discomfort23.03.03.006-Not Available
Skin exfoliation23.03.07.003-Not Available
Skin irritation23.03.04.009-Not Available
Swelling08.01.03.015-Not Available
Swelling face08.01.03.100; 23.04.01.018; 10.01.05.018-Not Available
Urticaria23.04.02.001; 10.01.06.001-
Skin burning sensation23.03.03.021; 17.02.06.009-Not Available
Inflammation10.02.01.089; 08.01.05.007-Not Available
Application site exfoliation12.07.01.022; 08.02.01.022; 23.03.07.007-Not Available
Keratosis pilaris23.01.01.002-Not Available
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